Tal Shechter

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Homogenization and the Industries That Use It

Posted by Tal Shechter on May 29, 2018 2:00:00 PM

bee2Many people go to a local store to buy food, personal care products, medicine and other items. However, most of us don’t spend any time considering what went into the production of these items. In many cases, it likely involved homogenization.

Homogenization is a process utilized for particle size reduction. It works by forcing a sample through a narrow space, and multiple forces, including turbulence and cavitation in addition to high pressure, can act on the sample to create a high-quality product. It can be used on many different types of material, such as plant, food, soil, tissue and more. Plus, it provides benefits for multiple applications, such as high-pressure pasteurization, dispersions, micro/nano emulsions and cell disruption.

Although many other types mixing machines exist, homogenizers are scalable, and their use of multiple mechanical forces instead of just one results in stable, uniform and consistent products. They are used in a wide variety of research and scientific uses and by many industries that require the use of active ingredients because they reduce active ingredients to a small enough size to ensure a thorough dispersion throughout the medium produced.

Pharmaceutical

Powerful mixing and particle size reduction are key techniques among pharmaceutical products. In the pharmaceutical industry, researchers use homogenizers during laboratory research and in clinical trials and manufacturing for products including vaccines, antibiotics, cancer treatment and medicinal creams. Benefits of homogenization for pharmaceutical products include improve delivery of active pharmaceutical ingredients, increased digestibility, lengthened shelf life and improved reliability in manufacturing settings.

The most important uses for homogenizers in the pharmaceutical industry are particle size reduction, scaling for drug development and synthesis of essential drug components. Though other mixing methods exist, homogenization is the most scalable, resulting in increased cost savings, lower time requirements and a decrease in the likelihood of failure for the product for which its used.

Food and Beverage

Many people identify the use of homogenization in the food and beverage industry with milk; it gives milk a longer shelf life and makes it more stable and visually pleasing. Homogenization is primarily used in the food and beverage industry to help manufacturers improve the composition and quality of their products and ensure their end products meet standards for visual appearance, texture and taste. 

Because homogenization utilizes pressure instead of heat, valuable nutrient content and flavor are preserved, chemical structures are stabilized and food processing outcomes are improved. It is a preferred method for producing emulsions, suspensions and other products that require a liquid suspended in another liquid or a small particle size. These products include mayonnaise, ice cream, cream liqueurs, salad dressings, dairy products and more.

Biotech

The biotech industry is comprised of the fields of cellular biology and molecular biology. Homogenizers are most commonly used in this industry to achieve effective cell rupture, enhanced particle size reduction and nanoparticle production. Although they decrease particle size, they ensure that a composition is equal throughout without compromising the overall molecular makeup of the sample.

Homogenizers also can be used to create cost effective medicines, modify microorganisms, synthesize new chemicals and develop alternative biofuels. In the case of cell disruption, they allow for a variety of cells, including E. coli, yeast, bacteria and delicate animal tissues, to be ruptured to recover the contents of essential cells.

BEE International: First on the Road to Reliability

BEE International offers homogenizers that are both high-quality and reliable. Our line of equipment is suitable for virtually every industry and can work in just about any environment. Contact us today to learn how our products can maximize your homogenization processes.

To learn more about 7 key factors to consider when choosing a cell lysis method, no matter the industry you're in, download our FREE eBook:

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Suspension vs. Colloid: How Do They Differ?

Posted by Tal Shechter on Dec 20, 2017 11:30:00 AM

suspension vs colloidAs we’ve outlined in recent blogs, homogenization is a process utilized for particle size reduction and works by employing mechanical force to break down particles or droplets in a liquid into smaller and more uniform sizes. The result of homogenization is a dispersion, wherein fine particles of one substance are scattered throughout another substance. Furthermore, dispersions are able to be classified by the sizes of these scattered particles: solutions, suspensions and colloids. In this blog, we’re focusing on the difference between suspension and colloids.

Suspensions

Simply defined as a heterogeneous mixture of two substances in which one is dispersed into the other, suspensions involve particles larger than those found in solutions, typically over 1,000 nm. The bigger particles of a suspension usually settle or separate out of a mixture upon standing or are able to be filtered out, although not through filter paper. Gravity is able to pull the visible particles in a suspension down if undisturbed, and they will stay that way unless being actively mixed. Examples of suspensions include oil and water, dust or soot in air, sand and water and muddy water.

Colloids

Although a heterogeneous mixture of two substances like suspensions, colloids involve particles from 1-1,000 nm that do not separate upon standing and cannot be separated by filtration. The particles in a colloid land in size between those in a solution and a suspension and may be solid, liquid or gas. The two parts in every colloid mixture are its particles and the dispersing medium, and the particles are spread evenly in in the medium, which can also be solid, liquid or gas. Examples of colloids are foams (shaving cream, Styrofoam), gels (gelatin, jelly), emulsions (mayonnaise, lotion), aerosols (fog, insecticide spray, smoke) and sols (shampoo, gemstones).

Even though the particles in a colloid are very small in size, they can be seen through a process called the Tyndall Effect, the effect of light scattering in colloidal dispersion while showing no light in a true solution. This effect is used to determine whether a mixture is a true solution or a colloid.

Colloid mills, like homogenizers, are able to process particle reduction formulations, although each is preferential for certain applications. They are best used for samples comprised of solids immersed in a liquid suspension or a liquid suspended in another liquid because they can enhance the stability and/or reduce the size of suspended particles.

Overview

In summary, following are some of the main differences between a suspension and colloid:

  • Particles in a suspension are usually more than 1,000 nm, while those in a colloid range from 1-1,000 nm.
  • Unlike those in a suspension, particles in a colloid do not separate when sitting still.
  • The particles in a suspension may be separated by filtration unlike those in a colloid.
  • Colloids are able to scatter light, but suspensions cannot transmit light.
  • Particles in a suspension can be seen by the naked eye, but those in a colloid must be viewed using a light microscope.

BEE International: The Clear Choice for High-Pressure Homogenizers

At BEE International, we not only offer a multitude of high-pressure homogenizers to handle almost any task in a laboratory, pilot plant or industrial setting, we help you sort through the technical jargon to find equipment that best addresses your specific needs. Our line of equipment is suitable for virtually every industry and can work in just about any environment, letting you focus on other important projects. To learn more about our technology and products, please contact us today!

If you’re interested in learning more about how you can break down particles in the best way possible, download our free eBook “How to Achieve Efficient & Consistent Particle Size Reduction” today:

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How Do Inline Mixers Work Differently Than High-pressure Homogenizers?

Posted by Tal Shechter on Dec 1, 2017 11:30:00 AM

inline mixersWhen they hear the term “homogenization,” many people think of milk. In fact, one of the first applications of homogenization came in the processing of milk. Derived from the Greek word “homogenos” (homos meaning same and genos meaning kind), it is defined as the process of reducing the particle size of an object and is also known as micronization.

Homogenization works by forcing a sample through a narrow space through multiple mechanical forces, thereby producing a stable and consistent product. Easily scalable, it is used by multiple industries, including pharmaceutical, biotech, cosmetic and food, in order to optimize their finished product.

Under the umbrella of homogenization lie two different methods: inline mixing and high-pressure homogenization. Read on to learn the differences between how the two work and advantages associated with each.

Inline Mixing  

Positioned within the production line and aligned with the flow of product, inline mixers consist of a stationary stator and an inside rotor that turns at high speeds. The rotor–stator device is contained in a casing with an inlet at one end and an outlet at the other, and the rotor is driven through a seal. Mixing occurs when a sample is drawn in through one of the mixing heads while the blades rotate and is then expelled at a high velocity through an opening in the stator. The inline term comes into play around the mode of sample entry into the mixing chamber.

Inline mixers feed and output material in a continuous stream, allowing material to often be perfectly hydrated, emulsified or homogenized in a single pass. They differ from other types of homogenization wherein large amounts of ingredients are mixed in a standalone unit before going through the homogenization process. Designed to handle all types of tasks, including emulsifying, suspending, dispersing, blending and more, inline mixers are suitable and useful for applications where larger quantities are needed for production and continuous processing and homogenization is needed during the manufacturing process. In addition to being faster than their high-pressure counterparts, they allow for a more controlled and continuous mixing environment, improve yields, use less energy and increase capacities.

High-pressure Homogenization

Whereas inline mixers rely on rotor/stator shearing action, high-pressure homogenizers force a sample through a narrow space using force and high pressure, thereby reducing particle size or lysing cells. They consist of a high-pressure pump and a disruption unit which enable a continuous homogenization. The higher the amount of energy applied during the homogenization process, the smaller the particle size or the more complete the cell lysis. The pressure along with the action of multiple forces yields impactful results in only one or two passes. Benefits of high-pressure homogenization include consistency in composition of products, greater stability of final products and decreased cost. Also high-pressure homogenizers allow users to set operating parameters - pressure, temperature, number of passes, valve and impingement design and flow rate – for a particular homogenization.

BEE International: Your Homogenization Equipment Headquarters

At BEE International, we offer a wide selection of homogenizers that meet the needs of manufacturers across multiple industries, including cosmetic, pharmaceutical, biotech and more. Our products can help enhance your production, improve product quality and streamline your operations, all in combination with our unmatched customer service. Contact us today to learn more about our homogenization equipment and find out what product(s) is best suited to your business needs.

For more information on particle size reduction and how to achieve efficient and consistent results, download our FREE eBook:

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What are Inline Homogenizers Used For?

Posted by Tal Shechter on Oct 30, 2017 11:30:00 PM

Business man looking at wall with a bright question mark concept-222794-edited.jpegOne important question to answer when beginning any manufacturing project requiring homogenization, micronization, or particle size reduction is an obvious one: what is homogenization, and what are homogenizers used for? Finding out the answers to these two important questions is an important first step in determining the type of homogenizer to purchase and ultimately use.  Various types of homogenizers exist, all with a multitude of pros and cons. In this article, we will focus on discussing one especially popular type of homogenizer -- the Inline Homogenizer.

Inline Homogenizers are designed to handle all types of tasks, including emulsifying, suspending, dispersing, and blending. These homogenizers are used in a variety of industries, including pharmaceutical, cosmetic, biological, and chemical. What makes inline homogenizers unique? One key feature is the fact that they are positioned within the production line, aligned with the flow of product.  Inline homogenization is different from other types of homogenization, such as batch homogenization, where large amounts of ingredients are mixed in a standalone unit before going through the homogenization process.

Inline homogenizers are suitable for applications where larger quantities are needed for production. Since they are able to be installed right on the production line, they are especially useful for applications where continuous processing and homogenization is needed during the manufacturing process.

The benefits of inline homogenization are endless. Not only is inline homogenization a faster process, especially in situations where larger quantities are being produced, it is also a more economical option, since additional mixing tanks and vessels are usually not needed. Inline homogenization also ensures consistency throughout a production run, since homogenization is occurring continuously on the production line.

BEE International offers a wide variety of inline homogenizers to meet the need of virtually any industry. Our Laboratory, Pilot and Industrial Homogenizers are suitable for all production needs, from small scale R&D applications up to full scale, 24/7 industrial operations. Our DeBEE 4000 homogenizer offers the following features and benefits:

  • Complete Automation, Compliance, and Production Capacity of 120 LPH and up
  • Multiple Vertical Process Intensifiers
  • An advanced, user-friendly interface
  • CE Compliant
  • Pharma/Bio/Food Sanitary
  • Synchronized Pump System for Constant Pressure
  • Advanced Data Collection and Gathering
  • Clean in Place (CIP)
  • Programmable Maintenance Schedule with Alarms
  • In-line Spare Intensifier
  • User Management
  • Data Trending

For more information on the Inline Homogenizers in our assortment, as well as our full suite of homogenization equipment, please contact us. We are looking forward to assisting you with your next homogenization project!

Need to Efficiently & Consistently Reduce Particle Size In-Line?

Many of our manufacturing partners that use inline homogenizers need to reduce the particle size of their application in order to pass it on to the next processing stage. With a variety of particle size reduction techniques, including homogenization, how can you find the best method? Check out our free eBook “How to Achieve Efficient & Consistent Particle Size Reduction” and learn which method is best for you:

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3 Advantages of Homogenizers for the Pharmaceutical Industry

Posted by Tal Shechter on Aug 23, 2017 11:30:00 AM

homogenizer for pharmaceuticalHomogenization – also known as cell fractionation or micronization – is the process of dividing particles into microscopic sizes, ranging anywhere from 0.5 microns to 2 microns, depending on the application. Homogenizers play an important role in the pharmaceutical industry, and are commonly used for dispersions, emulsions, particle size reduction, and cell rupture.

Keep reading to discover the advantages of homogenizers for pharmaceutical products in the ever-growing pharmaceutical industry.

1. Reduced Particle Size

Effective homogenization results in a smaller particle size and more even distribution of active ingredients. For topical pharmaceutical products, such as medicated creams, lotions, and ointments, this allows for those medications to absorb more rapidly into the skin. A reduction in particle size increases the surface area of critical (and often expensive) active ingredients, which allows for an even dispersion of the active ingredients in the product, which increases efficacy of pharmaceutical products and lowers cost as well.

2. Increased Stability of Pharmaceutical Products

High-quality homogenizers have the ability to reduce the particle size of critical active ingredients, which in some cases can help improve the stability of these otherwise unstable active ingredients. Some critical active ingredients used in the pharmaceutical industry are solid at room temperature, and only moderately soluble in water or organic solvents. Effective homogenization can reduce these otherwise difficult to work with active ingredients into a small enough size that they have increased solubility in these mediums, many of which can work further to increase the shelf life and stability of the active ingredients.

3. Increased Reliability in Manufacturing Settings

BEE International has a number of first-class homogenizers that can meet the needs of manufacturers in the pharmaceutical industry. Our industrial homogenizers are designed for cGMP manufacturing, and offer reliability suitable for all industries, including those with a 24/7 operating schedule. Our proprietary software offers touch screen guided operation, data collection, security, on-line maintenance schedules and alarms, and configurable recipes and capacities.

BEE International industrial homogenizers and high pressure homogenizers are manufacturing pharmaceutical, chemical, life sciences, food, cosmetic products, and more. Contact us today to discuss the benefits our homogenizers can bring to manufacturing your company’s products. You can also download our free eBook, “Advantages of BEE Homogenizers for the Pharmaceutical Industry” here.

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Local vs. Systemic Steroids: What's the Difference?

Posted by Tal Shechter on Jun 13, 2017 2:30:00 PM

Local vs. Systemic SteroidsWhen most people think of steroids, images of elite athletes using synthetic hormones to gain a competitive advantage may come to mind. However, steroids – more often referred to as corticosteroids in medical circles – are often used to serve a very different purpose. There are numerous varieties of corticosteroid medications, including cortisone, methylprednisolone, and prednisone.

Steroids work by both reducing inflammation and decreasing immune system activity, and they are commonly used to treat a variety of diseases, including rheumatoid arthritis, eczema, asthma, and a host of other inflammatory ailments.

Steroids come in several different forms – local and systemic.  The form of steroid used is dependent on the ailment that is being treated, as well as the desired outcome.

Local steroid medications are best suited for ailments where a targeted approach is desired. These types of steroids can be introduced directly to the area in question and include eye drops, ear drops, skin creams, and joint injections.

Systemic steroids are best suited for ailments that require treatment throughout the entire body. Systemic steroids circulate throughout the bloodstream and reach every area of the body. They include oral medications as well as medications that are delivered intravenously or intramuscularly.

For both local and systemic applications, homogenization is an important process step to consider in industries that manufacture steroid-containing topical creams, ointments, and intravenous drugs.

In all applications, the even dispersion of active ingredients is critical to ensuring efficacy and decreasing manufacturing costs. Oral medications, for example, require homogenization and micronization of particles to ensure consistency throughout the product. Similarly, systemic steroids require the use of a homogenizer to ensure even dispersion and dissolution of the particles that make up the active ingredients.

BEE International offers a number of homogenizers that meet the needs of manufacturers across multiple industries, including cosmetic, pharmaceutical, and biotech. Our homogenizers can meet the needs of virtually any environment – from small R&D settings and pilot plant operations all the way to 24/7 manufacturing environments.

For small sample sizes, as are often seen in laboratory and R&D settings, our Nano DeBEE is an excellent choice. This mechanical homogenizer uses multiple forces, including cavitation, turbulence, and pressure to create microscopic particles that can easily be dissolved in a variety of mediums, including liquids, creams, and organic solvents.

Contact us today to discuss the numerous benefits our homogenizers can offer to manufacturing your company's products. 

Also, be sure to check out our FREE eBook on how to achieve efficient and consistent particle size reduction

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Choosing the Right Pilot & Industrial Homogenizer

Posted by Tal Shechter on Apr 18, 2017 12:30:00 PM

choosing right pilot and industrial homogenizerHomogenization, also known as particle size reduction or micronization, is a technique that is widely used across a number of industries: cosmetic, food, pharmaceutical, and biotech. This powerful (and useful) technique allows manufacturers to create uniform creams, visually pleasing sauces, and effective pharmaceutical painkillers, just to name a few applications. And without the innovative technology found within homogenizers,  few of the aforementioned products would be as readily available as we’ve come to expect.

With that, it is no surprise that the task of choosing the right homogenizer for the job is an often daunting task. With so many options on the market to choose from, it is easy to get overwhelmed. However, if certain key points are kept in mind, choosing the right homogenizer for your pilot or industrial plant can be simple. Continue reading to learn more about the pilot and industrial homogenizers offered by BEE International.

DeBEE 2000 Pilot Plant Homogenizers

The DeBEE 2000 line of homogenizers represent the smallest available units that offer all available process configurations, including dual feed, dual jet, and automatic clean in place (CIP) technology.  These homogenizers also offer a number of powerful validation packages, as well as hazardous environment protection, feed solutions, and additional process monitoring.

DeBEE 3000 Industrial Homogenizers

The DeBEE 3000 line of homogenizers are our entry level production scale models, suitable for both laboratory work as well as scaled up production work. No matter the needs of your industry, the DeBEE 3000 line of homogenizers are suitable for your process. These homogenizers offer unmatched particle size reduction with maximum efficiency for micro/nano emulsions and particles, as well as the highest yield in cell rupture in the shortest amount of time.

DeBEE 4000 Automated Industrial Homogenizers

The DeBEE 4000 line of homogenizers represent the most powerful line of homogenization equipment that BEE International has to offer. This series of equipment offers the highest levels of process controls and automation, as well as integration with plant controls and compliance with CFR 21 part 11 requirements. In addition to other powerful benefits, these homogenizers offer various security modes and authorizations, alarms to ensure system safety and the correct course of action, SCADA compliance, and sanitary design and features suitable for even the most stringent of fields.

To learn more about the line of homogenizers offered by BEE International, please contact us today. We look forward to working with you on your next homogenization project.

For more information on particle size reduction and how to achieve efficient and consistent results, download our FREE eBook:

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How the DeBEE 2000 Can Benefit the Manufacturing Process

Posted by Tal Shechter on Mar 23, 2017 12:30:00 PM

DeBEE 2000Homogenization is used in a number of important industries, including cosmetic, food, pharmaceutical, and biotech. This process is more simply known as particle size reduction, and occurs when a particle is made smaller. This simple act has countless benefits: increased quality of texture, taste, and appearance, tissues and particles that are more readily studied in laboratory settings, and lower production costs. With all of these benefits (and many more!) it’s no wonder that more and more industries are looking to get involved in this powerful process by purchasing a homogenizer for their industry.

However, before taking on this task, it is important to understand the options that are available. BEE International is here to help! BEE – short for Best Emulsifying Equipment – stays true to its name with a number of machines that can help with the process of homogenization. Our homogenizers are well suited for virtually any application and just about any setting, from a smaller laboratory or R&D setting, to pilot plants, all the way to large scale manufacturing plants.

One of our more popular laboratory scale models is the DeBEE 2000. What does this powerful piece of equipment do? How can it help in your industry? What benefits and features does it offer? Continue reading to learn the answers to all of those questions and more. 

The DeBEE 2000 is designed to facilitate process development in a laboratory or R&D setting.  This series includes the DeBEE 2000-45-30, DeBEE 2000-45-60, DeBEE 2000-30-60, DeBEE 2000-25-100, and DeBEE 2000-20-120 models. The technology contains a proprietary homogenizing cell that allows for unmatched results in fewer passes. The DeBEE 2000 series is also well suited to produce results that are not just repeatable, but scalable as well. Other features include:

  • Easy to clean
  • Variable operating pressure up to 45,000psi
  • Modular design for lower cost replacement parts
  • PLC control and monitoring for simple operation
  • Constant process pressure for tighter product distribution
  • Ability to control cavitation, pressure, shear, and impact
  • Adjustable back pressure
  • Stainless steel enclosure
  • Dual feed
  • Dual jet
  • Automatic Clean in Place (CIP)

To learn more about the DeBEE 2000, as well as how we at BEE International can help with your next homogenization project, please contact us today. Our free product guide that explains more of the features in detail is available for download here.

For more information on how to achieve efficient and consistent particle size reduction results, download our FREE eBook:

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Sonication Cell Lysis: How Does it Compare to Homogenization

Posted by Tal Shechter on Mar 9, 2017 12:30:00 PM

sonication cell lysisHomogenization, also known as micronization or particle size reduction, is an important process step that is utilized in a variety of industries, including pharmaceutical, biotech, cosmetic, and food. With benefits like improved taste, texture, and appearance, its no wonder that more and more industries are looking to purchase a homogenizer for their manufacturing needs!

However, before purchasing your next homogenizer, it is important not only to know what your desired end use is, but the capabilities of the homogenizers in today’s marketplace. One question that is frequently asked regards the capabilities of homogenizers versus a sonicator. If you are interested in learning more about sonication cell lysis and how it compares to homogenization, you are in the right place! Continue reading to learn more about sonication cell lysis, how it compares to homogenization, and what BEE International has to offer in the way of high quality, high pressure homogenization equipment.

Sonication is defined as the act of applying sound energy to agitate particles in a sample. It is used for various purposes, including cell lysis, and it is a very powerful technology with both chemical and physical effects. Sonication serves multiple purposes, and is often used for the production of nanoparticles, such as nanoemulsions, as well as nanocrystals, liposomes, wax emulsions, and extractions of compounds such as plant oils and antioxidants.

Sonication works to lyse cells very quickly, with most methods taking between 15 seconds and 2 minutes. The intensity of sonication is quite easy to adjust, allowing for gentle or abrupt disruption of cell membranes. The temperature and length of sonication can also be adjusted.

Homogenization, on the other hand, involves the forcing of cells or tissue suspensions through a narrow space, which shears the cell membranes. Due to the high pressures associated with homogenization, fewer passes are needed to completely disrupt the cells, making homogenization a quicker (and oftentimes easier) choice for the lysing of cells.

BEE International offers a variety of homogenization equipment to suit virtually any need. Our homogenizers are suitable for laboratory and research & development use, as well as pilot plant and industrial use. Our homogenizers also offer the following features and benefits:

  • Easy to clean with CIP (Clean in Place) technology
  • Variable operating pressure from 5,000-45,000 psi
  • Modular design for lower cost replacement parts
  • PLC control and monitoring for simple push-button operation

Please contact us today to learn more about the homogenization equipment that we have to offer. We look forward to working with you to optimize the homogenization process for your industry.

For more information on cell lysis methods and how to choose the right one, download our FREE eBook:New Call-to-action

Microemulsions as a Drug Delivery System

Posted by Tal Shechter on Mar 7, 2017 12:30:00 PM

drug-delivery.jpgHomogenization, also known as particle size reduction, is a technique that is gaining popularity in numerous industries, including pharmaceutical, cosmetic, and food. In the pharmaceutical industry, where production of drugs, antibiotics, and other essential medications are paramount to the success of the industry, it is important to understand one important concept: microemulsions. To learn more about microemulsions – what they are, how they work, and how they are critical to the success of the pharmaceutical industry – continue reading.

Microemulsions are defined as clear, thermodynamically stable, liquid mixtures of oil, water, and a surfactant – a compound that lowers surface tension. While the aqueous phase of a microemulsion may contain salts or other ingredients, the oil phase is often a mixture of olefins and hydrocarbons. Microemulsions form upon mixing of the components, and do not require the high shear that is often necessary in the formulation of typical emulsions.

Microemulsions have a number of important uses, including (but not limited to) the following applications:

  • Water-in-oil microemulsions for dry cleaning processes
  • Floor polishers and cleaners
  • Personal care products such as creams and lotions
  • Pesticide formulations
  • Drugs

Microemulsions also have other applications, including the creation of polymers. During this process, the transport of free radicals, monomers, co-surfactants, inhibitors, and other species occurs across the aqueous and organic phases of a system.

In the world of drug delivery, self-microemulsifying drug delivery systems, which can be described as isotropic solutions of oils and surfactants that form oil in water microemulsions when they are introduced into an aqueous medium, can improve a number of processes. For example, when presented as capsules, these drug delivery systems can improve the absorption of active ingredients within the body. In addition, with active ingredients that are not water soluble, microemulsions can help resolve that issue, making drugs, antibiotics, and other products created by the drug industry more bioavailable to the end consumer.

BEE International offers a number of homogenization equipment that can help with the formation of microemulsions. Our laboratory homogenizers, including the Nano DeBEE, Mini DeBEE, and Micro DeBEE, are well suited for this application, as well as other applications within the research and development community. Other features and benefits of our laboratory homogenizers include:

  • Maximum operating pressure of up to 45,000 psi
  • Maximum capacity of up to 400 mL/min
  • Ability to create emulsions, dispersions, and microemulsions
  • Capabilities for cell rupture and liposome work

To learn more about what BEE International has to offer, please contact us today.

For more information on cell lysis methods, download our FREE eBook:

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