Creating Stable Dispersions with Homogenizers

Posted by Deb Shechter on Jan 3, 2017 12:30:00 PM

create_stable_dispersions_with_homogenizer.jpgHomogenization, also known as micronization or particle size reduction, is an incredibly common process that is shared by numerous industries, including pharmaceutical, biotech, cosmetic, food, and drug. In the cosmetic industry, for example, homogenization is used when an even mixture — or dispersion — of an active ingredient is desired within a lotion or cream.

The first step to creating an even dispersion is ensuring that solids are efficiently mixed with liquids. This task is not always an easy one, and comes with its own sets of challenges:

  • Instability
  • Agglomeration
  • Inability to Reduce Particle Size
  • Contamination

BEE International Equipment 

At BEE International, we offer a high quality line of homogenizers that can meet the needs of your industry while avoiding the common occurrences and challenges that come with the field of homogenization. Our systems are designed to produce even dispersions and emulsions, and are suitable for virtually every application, from small scale laboratory applications all the way to pilot plants and 24/7 industrial operations. 

Our laboratory homogenizers include the Nano DeBEE, Micro DeBEE, and Mini DeBEE, which are perfect for a smaller laboratory setting and offer capabilities for emulsions, dispersions, cell rupture, and more. Our line of laboratory homogenizers offer these additional benefits:

  • Capacity of up to 400 mL/min and 22 L/hr
  • Maximum operating pressures of up to 45,000 psi (3,100 bar)
  • Equipped with spare parts and tools
  • Results are scalable and repeatable
  • Easy to clean, use, and maintain

Our pilot and industrial homogenizers offer even more flexibility, and are suitable for the ever-growing needs of pilot plants and industrial applications. Our pilot plant and industrial homogenizers include the DeBEE 2000, DeBEE 3000, and DeBEE 4000; these homogenizers come equipped with our unique intensifier technology, and offer unprecedented reliability and versatility. Other benefits include:

  • Constant pressure with electronic synchronization
  • Numerous cylinder sizes available to meet pressure capacities
  • Unique Clean in Place (CIP) technology
  • PLC controlled homogenizers
  • Synchronized pump system for constant pressure
  • Menu guided maintenance and calibration

Other features of our homogenizers include:

  • Better particle packing
  • Dense and uniform distribution of materials
  • Improved bioavailability of pharmaceutical suspensions
  • Elimination of un-dissolved polymer components

Contact us today at BEE International to learn more about our line of high pressure homogenizers, and how our equipment can work to meet the needs of your industry. Our FREE eBook, “7 Key Factors to Consider When Choosing a Cell Lysis Method” is also available for download:

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Homogenizer, Dispersions