David Shechter

Recent Posts

How to Guarantee Water Soluble Cannabinoids for Beverages

Posted by David Shechter on Sep 29, 2021 1:05:00 PM

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Cannabinoids, chemical compounds found in the cannabis plant, are naturally fat soluble, meaning they are dissolvable only in nonpolar solvents and, thus, not capable of mixing with water. It’s a major problem that often makes the manufacture of cannabis-based beverages difficult since cannabinoids can’t be broken down and mixed with other ingredients naturally for any sustained amount of time. Cannabis-based beverage products, for instance, work faster, taste better and last longer only when they are able to be mixed properly with — read: dissolved completely within — other ingredients. Leaving cannabinoids in their original oily state, then, makes it impossible to guarantee the bioavailability, stability or longevity of cannabis beverages. Luckily, manufacturers have options. Here’s how you can create water soluble cannabinoids for beverages and, therefore, always ensure that your cannabis drinks are of the highest quality:

What are Water Soluble Cannabinoids for Beverages?

Technically, there are no “true” water soluble cannabinoids. What we actually mean when we use the term “water soluble cannabinoids for beverages” is really just “cannabinoids that have been reduced to the smallest-sized particles so that they can be thoroughly mixed with a liquid substance.” With this in mind, the trick becomes finding a way to break down cannabinoids into such small pieces that they can be used to manufacture cannabis beverages with maximized flavor and potency.

Using Emulsions to Create Water Soluble Cannabinoids for Beverages

As mentioned, if cannabinoids are left in their natural state, cannabis-infused drinks would need to be shaken and then immediately consumed. It’s not unlike an oil-based salad dressing that has to be shaken before used. This is never ideal, however, since shaking a product can actually degrade it: carbonated drinks lose their bubbles, for example, or ingredients get unevenly distributed, making the drink taste funny, look cloudy and/or rendering it unable to provide a consistent dose of active ingredient(s). Furthermore, because the cannabinoids are still basically fat molecules which have been only temporarily suspended in a liquid, the body must still process them through the digestive system, a much longer process compared to that of water soluble cannabinoids dissolving directly into mouth, stomach and intestinal tissues. 

To solve the problem, manufacturers need to create water soluble cannabinoids via emulsification. Emulsification is the process by which normally immiscible substances are mixed together so that separation can’t occur. There are several different types of equipment that can facilitate emulsification, but the most effective and efficient one is a BEE International high pressure homogenizer. BEE stands for Best Emulsifying Equipment.  Our high pressure homogenizers create stable emulsions that guarantee water soluble cannabinoids for beverages each and every processing run.

The BEE International Advantage

Most emulsifying processing equipment utilizes only one or two forces to physically break apart and mix samples. BEE International high pressure homogenizers, however, utilize a combination of forces, including turbulence, shear, cavitation, impact and high pressure, that more forcibly reduces a sample’s particle size, creating larger surface areas to which bonding can occur. The result: shelf stable mixtures with increased potency and bioavailability. In addition, our patented mixing technology eliminates the need for pre-mixing and includes customizable options for the combination of forces, as well as the intensity and duration of operation, allowing manufacturers to manage the production of water soluble cannabinoids for beverages in the fewest amount of passes, saving them time and money.

To learn more about using BEE International homogenizers to create water soluble cannabinoids for beverages, please contact our team today.

You might also wish to download our free eBook, “3 Reasons Why High Pressure Homogenization Improves Cannabis Products” for additional information.

How Cavitation is Used in Chemical Engineering

Posted by David Shechter on Aug 27, 2021 2:05:00 PM

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Cavitation is the rapid expansion and implosion of vapor-filled bubbles (or “cavities”) within a liquid substance. These cavities form when intense vibration within the liquid breaks its natural bonds and causes its ambient pressure to become lower than its vapor pressure. In many instances, cavitation is seen as a problem, causing functional changes in both natural and manmade processes that make reliable and consistent operational results impossible. In other cases, however, cavitation can be harnessed for specific manufacturing benefit, delivering products that are more effective — in both application and cost — than those made without it. Chemical engineers, for example, rely on cavitation to homogenize particles within colloidal suspensions, thus enabling them to create a wide range of chemical products including polymers, plastics, pigments, paints, pastes, pharmaceuticals and more! Read on to learn how cavitation is used in chemical engineering:

Cavitation is Used to Reduce Particle Size

In many (perhaps even most) chemical manufacturing processes, substances need to be mixed in order to be useful. Thus, first and foremost, cavitation is used in chemical engineering as a way to reduce particle size so that one substance can be more thoroughly combined with another one. Think about it: it’s a lot easier to combine small, uniform pieces than it is to combine large, various-sized ones!

Cavitation is Also Used to Improve Cohesion 

Furthermore, smaller particles mean more surface area; more surface area means more opportunities for particles to interact with one another; and more interaction ultimately yields better — i.e., tighter — cohesion. Because of this, the implosions caused during cavitation inception can be intentionally harnessed during chemically engineered product processing as a way to disrupt the natural bonds of a substance, creating products with a tight distribution of smaller particles that subsequently improve their consistency, viscosity, texture, appearance and even bioavailability (when applicable)!

Indeed, the uniformity of particle size and the cohesion it facilitates combine to provide enhanced product stability, ensuring more effective and a lot longer lasting products than those created in other ways.

The BEE International Advantage

In the chemical engineering world, cavitation isn’t just a problem to be avoided, eroding pumps and interfering with mechanical operations. On the contrary, cavitation can be used for advantage in many chemical manufacturing processes; intentionally initiating cavitation during production allows manufacturers the ability to create extremely effective, reliable and shelf-stable products. And if they use a BEE International high pressure homogenizer, the results can be further compounded. 

Want to Learn More?

Our proprietary emulsifying cell technology ensures the scalability and customizability of all types of chemical processing, benefits a lot of equipment used to induce cavitation on the market today can’t guarantee, as well as requires fewer passes of product to deliver maximum effect, saving companies time and money. Finally, the high pressure with which our homogenizers operate destroys potential pathogens, ensuring that all products made with our homogenizers are safe and free of biological contaminants. To learn more about the advantages of using BEE International high pressure homogenizers to induce cavitation during chemical processing, please contact us.

An Introduction to Creating Colloidal Solutions

Posted by David Shechter on Aug 13, 2021 1:50:00 PM

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Mixing is an important part of many processes, affecting the quality of numerous man-made (and nature-made) products. In laboratory and manufacturing settings, mixing often determines the overall value of a product, as well; mixed inappropriately, a product could end up being useless, costing scientists and manufacturers alike a lot of wasted time and/or money and offering no significant or effective operational merit. Thus, it’s important to know the different types of mixtures and their associated benefits. In this post, we’re going to discuss colloidal solutions, a type of mixture wherein tiny particles of one substance (liquid, solid or gas) are suspended within another substance (liquid, solid or gas). Here’s what you need to know about colloidal solutions, including how they’re created and what their differences from other types of mixtures mean for the people who use them:

What is a Colloidal Solution?

Multiple kinds of mixtures exist (solutions, suspensions and colloids/dispersions) with each one involving a specific process for its creation. For this blog, we’ll consider a colloid mixture (also commonly called a “colloidal solution” or “colloidal dispersion”), which is a mixture of one substance into another such that neither can be separated from the other. However, unlike a true “solution,” a colloidal solution does not involve the dissolution of one substance into another. Instead, a colloidal solution is comprised of particles that are evenly distributed (but not dissolved) within a substance in such a way that they can not settle nor separate from the medium over time. The key to this type of mixture is ensuring that the substance being dispersed into the associated medium is broken into particles that are small enough that they can be — and will always remain — thoroughly mixed with the medium containing them. Mixtures that don’t remain combined are known as suspensions.

How to Create a Colloidal Solution

The first step in creating a colloidal solution is breaking apart the product to be dispersed into the medium. There are several ways to facilitate this process; chemicals can be used to break apart a product and/or physical force(s), such as agitation, stirring, pounding, grinding, etc. High pressure can also be used, and our team at BEE International believes that our high pressure homogenizers provide the best options on the market when it comes to particle size reduction for colloidal solutions. Our homogenizers combine a variety of forces (high pressure, shear, cavitation and impact) to ensure nano-sized particles result in the least number of passes. These extremely small particles are then able to be fully distributed throughout the medium, thereby effectively creating a colloid solution.

Why Colloid Solutions are Important

Colloids are valuable because they prohibit the separation of two otherwise immiscible products. The milk we drink; the paint we use; the makeup we wear; the drugs we take: these are all example of colloid solutions. Because very small particles have been mixed in just the right way, many of the foods, paints, polymers, pastes, cosmetics and pills (and more) that we consume are able to exist. Mixed properly, they are consistently more stable, lasting longer than they would otherwise, as well as more attractive, remaining fully combined so that they look and feel smooth and cohesive. When applicable, colloids are also better tasting with better bioavailability. These are all important benefits of colloidal solutions.

Want to Learn More?

Creating colloidal solutions is a critical process that affords us with many useful and vital products for everyday life. To effectively disperse products within a medium, manufacturers and scientists need reliable, effective equipment. We believe BEE International high pressure homogenizers (HPHs) offer the tightest distribution of the smallest sized particles in the least number of passes, making them the best option for the creation of colloidal solutions. To learn more about our HPHs and the advantages they offer for a variety of processes, please contact our team.

You might also wish to download our free eBook, "How to Achieve Efficient & consistent Particle Size Reduction,” for additional tips.

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High Pressure Homogenizers for Nanomilling for Bioavailability Enhancement

Posted by David Shechter on Jul 16, 2021 2:25:24 PM

unspecified_1Approximately 50% - 90% of existing and potential new drugs are poorly soluble. It’s a statistic with dramatic implications, since poor solubility inhibits the absorption of a drug’s active pharmaceutical ingredient (API), which renders less beneficial effects for the patients who wish to use them and less profitable results for the companies that try to sell them. Recent advancements in pharmaceutical development processes, however, indicate that using high pressure homogenizers for nanomilling dramatically improves the bioavailability of active drug ingredients, thus benefiting individuals and drug companies alike. Take a look:

What is Nanomilling for Bioavailability?

Drugs work better when they have a large surface area available for solvation. Think about a sugar cube dissolving in a cup of tea: a crushed cube will diffuse throughout the cup quicker than a lump. In much the same way, a drug whose active particles have been reduced to their smallest uniform size will disperse throughout the body better than a drug with larger particles.   

Nanomilling, then, is the process by which an API is reduced to particles less than 1000 nm in size. It’s also called wet media milling, and can be effectuated via several different techniques, but we believe high pressure homogenizers (HPHs) offer the most advantages when nanomillling for bioavailability. Here’s why:

High Pressure Homogenizers Minimize Contamination

High pressure homogenizers apply constant pressure to a product to break it into uniformly-size pieces. Other types of particle size reducers (such as bead mills, for example) use an actual grinding material (i.e., beads) to the facilitate particle reduction, agitating this material along with the product so that the product itself breaks apart. We believe HPHs, particularly those with BEE International’s propreitary pressurized pumping system, are far superior to bead mills and other wet media milling technologies specifically because they don’t introduce any foreign materials into the particle reduction process — just high pressure and the active pharmaceutical ingredient —  thus, posing little to no risk for contamination.

High Pressure Homogenizers are Faster

High pressure homogenizers supply a very intense and focused energy that enables quicker particle reduction than other processing methods. They are also highly efficient, enabling optimal particle size in the fewest passes, saving valuable production time and getting drugs — that actually work! — more quickly into the hands of the patients who need them!

High Pressure Homogenizers Allow for Targeted Particle Reduction

Because BEE International’s HPHs utilize a modular system that combines pressure, shear, cavitation and impact, many different configurations can be set up, each according to the specification of the product at hand. This means operators can customize their processes so that the exact particle size needed is produced during each run.

High Pressure Homogenizers Are Consistent and Versatile

The unique combination of forces used in BEE International high pressure homogenizers produces a tighter, more uniform distribution of particles and can be used for both inline and batch processing.

High Pressure Homogenizers Yield Scalable Results

The most beneficial type of processing equipment allows operators the ability to progress from the laboratory to production with no loss of reliability or efficacy. High pressure homogenizers allow customization of the particle size reduction process according to product volume so that the chemical integrity of active ingredient(s) is always the same.

High Pressure Homogenizers Are Easy to Clean

Finally, unlike bead mills and other types of homogenizers, high pressure homogenizers do not require manual cleaning. Inline cleaning processes permit routine (and nearly) hands-free maintenance that is not available with other nanomilling options.

Want to Learn More?

Utilizing high pressure homogenizers for nanomilling for bioavailability enhancement allows companies to produce more effective drugs and people the opportunity to take them. To learn more about what makes BEE International high pressure homogenizers the superior choice when nanomilling for bioavailability enhancement, please contact our team today.


You might also wish to download our free eBook, “Advantages of BEE Homogenizers for the Pharmaceutical Industry,” for additional information.

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What’s the Best Way to Lyse Bacterial Cells?

Posted by David Shechter on May 28, 2021 9:10:46 AM

the-benefits-of-a-laboratory-homogenizer-for-cell-lysisCell lysis is the process by which a cell’s membrane is ruptured so that the cell’s contents are released. It can occur naturally (such as when certain viruses cause infections that lead to cell rupture and death) or it can be induced artificially. In addition to scientists who wish to study and experiment with intracellular contents, and thus, must be able to control the cell lysis process, there are multiple industries (including, but limited to, the pharmaceutical, biotech, food and chemical industries) that need to lyse cells in order to make products. To ensure their products’ safety, quality and efficacy, these industries must intentionally disrupt cell membranes according to their own standards instead of waiting on any natural lysis sequences that mayor may not occur. Indeed, one of the most critical components of any manufacturing process is ensuring safety, removing all potentially harmful substances so that the wellness of consumers is always protected. To this end, many industries use artificial cell lysis to remove pathogens, of which some of the most frequently occurring are bacterialcells. The question then becomes: what’s the best way to lyse bacterial cells, essentially killing them and rendering them incapable of causing illness and disease? Here’s the short answer:

Bacterial Cell Lysis is Best Facilitated by BEE International High-Pressure Homogenizers 

While there are several ways to artificially lyse cells (sonication, chemical lysis and traditional homogenization, to name a few examples), there is only one method that is capable of lysing all cell types (including bacterial ones) and that is high-pressure homogenization. Specifically, our high-pressure homogenizers here at BEE International incorporate a patented Emulsifying Cell (EC) technology that combines shear, cavitation and impact forces so that the high-pressure homogenizing process always renders optimal results. Whether used in research, pilot or industrial settings, BEEI high-pressure homogenizers ensure the best processes for bacterial cell lysis because they:

  • Provide accessibility of intracellular proteins for extraction and solubilization.
  • Disrupt all cell types since users can alter pressure, flow and processing time, as well as the amount of cavitation, shear and impact forces, to get the best results for the type of cell they are disrupting.
  • Offer flexibility, allowing easy adjustment for different cell disruption strategies.
  • Deliver high yields in less time, which lowers Total Cost of Operation (TCO).
  • Possess scalable technology, which enables users to elevate from laboratory scale to pilot scale, while achieving reproducible results.
  • Support various sample sizes and permit users to adjust the widest variety of mixing forces.
  • Require minimal training and are easy to use, reconfigure, clean and maintain.

 

Want to Learn More?

To learn more about high-pressure homogenization and why it is the best method for bacterial cell lysis, please contact our team at BEE International. We believe our equipment offers superior quality and provides the best value for researchers and manufacturers alike. Our proprietary processes guarantee that our customers produce high cell rupture yields in the shortest amount of time across the widest variety of cell types. 

You might also wish to download our free eBook, “7 Key Factors to Consider When Choosing a Cell Lysis Method,” for additional information bacterial cell lysis.

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Why Homogenizers are Essential to CBD Processing

Posted by David Shechter on Jun 30, 2020 10:00:00 AM

CBDFor many business leaders, the CBD industry represents an exciting investment opportunity. Indeed, one major player opened 70 new CBD store locations in 2019 alone. And experts predict that the industry as a whole will continue to grow over the next few years. However, it’s important that businesses involved in CBD processing and the manufacturing of products like lotions, edibles, and extracts understand how to ensure efficient and uniform production standards. This is crucial for business reputation, customer satisfaction, and ROI. Here, we’ll explain why high-pressure homogenizers are essential to this process, and how CBD-based companies can benefit from using them: 

Cannabinoids

Cannabinoids are the chemical compounds found within the cannabis plant. Crucially, they represent the active ingredient in CBD products. In order to create a CBD product, manufacturers harvest cannabis flowers, reduce them to first unrefined and then refined oils, and then process the oil into a single compound known as cannabinoid isolate.  

The problem at the next, and final, stage of the process is that cannabinoids are hydrophobic –– meaning that they don’t mix with water. So it can be very difficult to evenly and efficiently incorporate cannabinoids into a finished CBD product. 

As such, CBD manufacturers must use emulsifiers to create oil-in-water emulsions involving cannabinoids. From there, they are able to form micro-emulsions, nano-emulsions, or liposomes, which are effectively combinations of hydrophobic and hydrophilic materials. Ultimately, this enables effective mixing of CBD and non-CBD compounds within a given product.

How Homogenizers Work

Generally speaking, the quality of an emulsion depends on the quality the mixing method employed. This is where high-pressure homogenizers stand above other mixing options. Most mixing equipment uses all of the three following methods to form stable emulsions: 

  • Impact –– high forces applied over a short period of time.

  • Slice/Tear ––  motion between adjacent layers of liquid.

  • Cavitation –– rapid pressure changes. 

High-pressure homogenizers are unique in that they employ all three methods at the same time. This ensures effective particle-size reduction –– a crucial aspect to quality control and production in any mixture. The smaller the particles are, the more even the mixture is and the higher its bioavailability becomes. 

Benefits to Using Homogenizers for CBD Processing

Because homogenizers so effectively emulsify and mix CBD substances, businesses are able to guarantee quality control every time they produce a new batch of products. The homogenization process eliminates “hot spots” –– or collections of CBD compounds within a mixture –– thus creating evenly distributed mixtures every time. 

What’s more, high bioavailability maximizes the potency of CBD products. So businesses are able to deliver high-quality products while using lower amounts of active ingredients. Bolstered bioavailability also contributes to faster-acting CBD products, and more stable CBD products that have a longer shelf-life. All told, high-pressure homogenizers can increase bioavailability by up to 75%.

In summation, using homogenizers to complete CBD processing boosts ROI, reduces costly inefficiencies, creates high-quality, potent, long-lasting products, and –– in all likelihood –– will improve customer satisfaction as well. 

Contact Us

BEE International has been a leading provider of high-pressure homogenization solutions for decades. Not only is our equipment cutting-edge and versatile, but we’ve also added cannabis-specific innovations to our process based on customer feedback. For more information, you can check out our eBook on cannabis products. Or, to get started with us today, contact us here.

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What Does a Homogenizer Do?

Posted by David Shechter on Jul 16, 2019 9:25:31 AM

What Does a Homogenizer Do?There are many types of homogenizers, from the basic kitchen blender and handheld, laboratory dounce homogenizer that use mechanical force to break apart and blend food or other “ingredients” to the numerous kinds of large, industrial homogenizers that rely on pressure to effectively disrupt and mix microscopic components of a sample. There are even ultrasonic homogenizers that use cavitation to produce similar results. But just what does a homogenizer do, you might wonder? How does it work?

 

While the specifics of how a homogenizer does what it does changes based on the composition of the materials on hand and the proposed intent of the product to be made, the basic premise of what it does is always the same. Thus, despite the fact that there are dozens of different types of homogenizers, all of them basically do the same thing: apply force(s) in order to separate the parts of one substance and thoroughly mix them with the parts of another.

 

Why Use Homogenizers?

Homogenizers are used to completely mix a solid, liquid or gas into another substance, but they also offer several other key benefits and, thus, are invaluable across numerous industrial, chemical, biotechnological and food manufacturing processes. Specifically, in addition to the aforementioned blending purpose, businesses use homogenizers to reduce the particle size of various types of substances; facilitate the elimination of pathogens in food products (also known as pasteurization); improve the stability, appearance and texture of chemical compounds (including things such as paint, makeup and medications); increase the bioavailability of pharmaceutical products; extend product shelf life; maintain consistent levels of quality; and reduce manufacturing costs.

 

In short, homogenizers enable companies to guarantee efficacy and efficiency no matter their application. Indeed, some homogenizers achieve results by agitating and stirring. Some do it by crushing and grinding. Others push suspensions through narrow passages, and some use pressure and impact. But regardless of the type of force used, all homogenizers aim to mix together two naturally immiscible substances so that any number of the above benefits can occur.

 

Ready to Learn More?

Homogenizers do a lot of different things, making them useful tools that foster a myriad of advantages across several separate industries. If you need assistance determining the type of homogenizer best suited to your needs, contact our team at BEE International. Our homogenizers combine high pressure with turbulence, cavitation, impact and shear forces, which, when coupled with our patented Emulsifying Cell (EC) technology, serves to improve manufacturing and laboratory processes and saves you valuable time and money.

 

And for additional information, feel free to download our complimentary eBook, “How to Achieve Efficient & Consistent Particle Size Reduction." In it, we detail how our proprietary in-line processing technology maximizes particle size reduction in fewer passes and helps you maintain cost-effective manufacturing practices.

 

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When is the Right Time to Purchase an Industrial Homogenizer?

Posted by David Shechter on Jun 12, 2019 9:00:00 AM

Industrial HomogenizerIn manufacturing terms, bigger is often better, especially if you’re talking about the equipment that companies need to process the products they sell. Indeed, profitability frequently depends on a company’s ability to meet consumer demand while simultaneously maintaining quality and safeguarding costs. Many accomplish this by utilizing large capacity processing equipment to render bigger outputs in less time. By increasing product volume, decreasing manufacturing duration and maintaining the integrity and reliability of both via automated (not manual) processes, companies in all types of industries can generate bigger financial gains.

 

For those industries tasked with creating homogenized products, large scale equipment can facilitate better micronization, better mixing and better scalability (i.e., better overall results). If you’ve ever struggled to meet the demands of your customers or to verify the accuracy, efficacy, constancy and consistency of your products, then investing in an industrial homogenizer will likely solve a lot of your problems. Here’s how you’ll know it’s the right time to purchase an industrial homogenizer:

 

You Have High Product Demand

Industrial homogenizers are created specifically for bulk processing. Whereas laboratory homogenizers are perfectly capable of (and generally preferred for) handling small batch loads, industrial homogenizers can accommodate large quantities of materials, making it easier for companies to process a lot of product in less time. If you’ve moved past the initial research and development stage and have a final product to mass produce, it’s the right time to buy an industrial homogenizer.

 

You Need Flexibility for Processing

An industrial homogenizer is usually more versatile than a laboratory homogenizer, with advanced options available for tailoring processing functions according to individual need. At BEE International, our industrial homogenizers incorporate our patented Emulsifying Cell (EC) technology, a linear process that guarantees scalability of results each and every run. Our machines also include proprietary software, the “most advanced, reliable, and versatile intensifier technology on the market” and an automation system that allows for continuous operation, advanced data collection and integration with plant controls, generating countless opportunities for customization.

  

You Want To Minimize Costs

Bigger machines can cost more and warrant more maintenance. However, our DeBEE 4000 industrial homogenizer model comes equipped with hydraulically-driven vertical intensifier pumps that effectively lower maintenance costs and a “unique CIP position [that enables] flow through the high pressure cylinder for faster and more thorough cleaning.” Both of these features help keep our machines running smoothly and cleanly. Oftentimes, smaller homogenizing systems become overstressed trying to accommodate the processing of an unrealistic load. This not only wears out the machine’s mechanics, it requires more labor, more maintenance and probably more repair, all factors that accumulate more expense in the long run. A BEE International industrial homogenizer can mitigate that problem.

 

You Must Verify Safety Compliance

Manufacturing plants are required to adhere to certain sanitary and safety guidelines. Thus, most industrial homogenizers support compliance with FDA, CGMP and 3-A standards. Our BEE International industrial homogenizers offer this feature, as well as additional ones meant to make cleaning machine parts easier and more effective so that you can adhere to industry standards with minimal disruption to the production process. You should purchase an industrial homogenizer if you are required to verify any trade and/or government guidelines.

 

Want to Learn More?

Homogenizers are essential expenses for companies needing to homogenize and/or reduce the size of the particles in their product(s). Industrial homogenizers, in particular, can help large companies meet manufacturing demand, validate quality and ensure product stability and performance. All our equipment comes with a two year warranty to further protect your investment, your time and the trust of the people you serve. Contact us to learn more.

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Homogenizer Mixer: 3 Benefits for Your Application

Posted by David Shechter on May 2, 2019 4:43:57 PM

homogenizer mixer benefitsMixers come in a variety of shapes and sizes, from the common wire sauce whisks found in most home kitchens to the large drum mixers used in many industrial plants. Choosing one type over the other really comes down to what and how much you’ll be mixing, as well as how often you’ll be doing it. For example, a whisk is an appropriate tool for mixing cake batter, but you’d never try to mix cement for your new patio with one. And if you own a commercial bakery, you’d probably want an electric heavy-duty floor mixer that’s capable of stirring enormous amounts of ingredients day after day instead of a tiny whisk you have to beat yourself.

Another type of mixer is the high pressure homogenizer. At BEE International, our homogenizers pull product through a proprietary system that produces a constant pressure up to 45,000 PSI and pumps out a “high-velocity jet strong enough to cut metal.” The jet then enters our patented “Emulsifying Cell (EC)” and combines with other forces to yield a final product that is thoroughly broken apart and blended. Unlike other types of mixers, a BEE International homogenizer is versatile across many different applications. Here’s why:

Smaller Particle Reduction

Different mixers use different forces to break apart particles. For example, stirrers and agitators use turbulence; sonic mixers use cavitation; high shear mixers use shear; bead mills use impact; and high pressure homogenizer mixers use pressure. High pressure homogenizer mixers effectively reduce product particle size on their own, outputting products with better sensorial and biophysical properties with longer shelf lives. However, BEE International homogenizer mixers combine high pressure with all of the aforementioned forces, facilitating a gentler cell disruption and even smaller particle reduction than any other one mixer type. Operators can adjust the duration, intensity and type of forces used in the mixing process, ensuring that the cell walls of different biological materials are lysed in ways that preserve their intercellular components and

create a "tighter distribution of smaller particles [...] in fewer passes." This not only improves manufacturing efficiency, it reduces manufacturing costs!

Stable Emulsions and Dispersions

In addition, high pressure homogenizer mixers are so adept at reducing particle size that they also more successfully combine materials that don’t normally mix. The unique variety of forces used in BEE International homogenizer mixers especially combine to generate clearer nanoemulsions in all liquid products (emulsions) and more uniform distribution of solids within “liquid solutions, suspensions and colloids” (dispersions). Other mixers that only use one type of force can’t get particles small enough to enable that benefit.

Improved Pasteurization Results

Similarly, while high pressure homogenizer mixers can be used to remove pathogens from various types of food, BEE International homogenizers have the added benefit of allowing hold times under pressure to be customized. This means manufacturers can achieve maximum pasteurization results for a variety of products with only one machine. It also means operators can target specific organisms by applying the least amount and length of pressure necessary to kill each one, thereby preserving other vital components of the final food product for better taste, nutritional value and appearance.

Want to Learn More?

High pressure homogenizer mixers offer manufacturers and researchers a variety of benefits. They produce stable products with longer shelf lives, improved bioavailability and better rates of dissolution. And they do it with less waste and less resources since high pressure homogenizer mixers require less chemical and thermal processing to achieve maximum results. If you want to save time and money while still making superior products, contact our team at BEE International. We are industry leaders in quality homogenizing systems and can help you pick the right equipment for your own distinct needs.

You might also wish to download our free eBook, “How to Achieve Efficient & Consistent Particle Size Reduction,” for more tips on maximizing your manufacturing processes (as well as your ROI) with high pressure homogenizers.

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Particle Size Reduction Equipment: Why Homogenizers Stand Out

Posted by David Shechter on Feb 9, 2019 10:00:00 AM

particle size reduction equipmentReducing large materials into smaller ones is a common and often necessary occurrence in the natural world. From the earth itself eroding to food being digested to rocks being broken into tools, the physical process of reducing something into smaller bits frequently permits advantages (or wonders!) that otherwise wouldn’t exist. Take, for instance, the splendor of the Grand Canyon or the awe-inspiring fact that our bodies can break apart food and air and water into life sustaining nutrients or the many ways humans have made valuable tools from rocks and wood and other resources. Indeed, the world’s very first tool — the hammerstone — was made by ancient hominids and served a purpose not unlike today’s own particle size reduction equipment: to turn something bigger into something smaller.

Modern particle size reduction equipment is categorized according to four basic types:

  • Crushers - which break apart large particles into smaller ones
  • Grinders - which further crumble crushed particles into powder
  • Ultrafine Grinders - which pulverize ground powder into pieces 1-50 micrometers in size
  • Cutters - which yield particles of a specific shape and size

Considering product hardness, consistency and volume (many machines are better suited for certain capacities), companies may use one or more of the equipment types. Many pharmaceutical companies, for instance, opt for ultrafine grinders that can reduce active pharmaceutical ingredients into superfine particles to increase bioavailability. Baby food and soup manufacturers, on the other hand, might need cutting capabilities to ensure that all food pieces in their products are similarly sized. Some manufacturers might use crushing techniques followed by grinding ones or run their products through one system multiple times. It really just depends on the overall purpose of the product being manufactured, the initial ingredient composition and how much money a company has to spend.

With all this in mind, savvy manufacturers started considering the use of high pressure homogenizers as a fifth alternative for businesses in need of particle size reduction equipment. Homogenizers effectively mix together two normally immiscible substances using high pressure. A happy result of the process: homogenizers also reduce particle size! For manufacturers looking to make an equipment investment that not only works, but works across numerous applications, a high pressure homogenizer has become a solid choice. Unlike traditional particle size reduction equipment that only makes use of one type of mechanical force, a high pressure homogenizer utilizes several different ones. And at BEE International, our proprietary system not only uses turbulence, cavitation, high shear and impact to break apart product, it also has modular components that can be customized for specific purposes. Turbulence and cavitation treatments can be altered, shear times can be reduced or lengthened and impact and intensity can be tweaked. So, just want does all this mean? 

The Benefits of Using High Pressure Homogenizers (HPHs) as Particle Size Reducers:

  1. HPHs produce tighter distribution of smaller particles.

  2. HPHs achieve better particle reduction in fewer passes.

  3. HPHs increase manufacturing efficiency.

  4. HPHs reduce manufacturing costs.

  5. HPHs help create products with longer shelf lives, increased bioavailability and improved sensorial and biophysical properties. 

Want to Learn More?

Homogenizers can be used for a lot more than milk production and laboratory tests. Manufacturers in nearly every industry can use them to accurately reduce product particle size with a flexibility unmatched by other equipment types. Contact our team at BEE International for additional information on the ways a high pressure homogenizer can streamline your manufacturing process, improve your product integrity and benefit your bottom line.

Please feel free to also download our free eBook, "How to Achieve Efficient & Consistent Particle Size Reduction,” for more tips.

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