Deb Shechter

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How Do Homogenizers Lyse Cells?

Posted by Deb Shechter on Oct 16, 2019 12:48:36 PM

how do homogenizers lyse cells?Cell lysis is the process by which cell membranes are broken down so that the contents within the cell can be studied and/or purified. It’s a critical part of many industrial and research enterprises, often providing the only means by which certain products can be made or used. There are several different ways to lyse cells (broadly categorized as either mechanical or non-mechanical) with each type dependent on the makeup of the cellular barrier, as well as the intended application of the cellular contents themselves. For instance, some cell lysis methods are highly destructive and, thus, not suitable in situations where the contents of the cell need to remain intact to be serviceable (such as during RNA and protein extractions). Others only work when applied to weaker cell barriers (such as animal plasma membranes vs. plant cell walls), and still others have to be combined with additional processes in order to effectively open the cell at all. The good news is that a variety of homogenizers can lyse cells under a variety of circumstances. Read on to learn more.

 

Mechanical Cell Lysis Options with Homogenizers

Mechanical cell lysis utilizes a particular force (or forces) to physically break apart a cell. It differs from non-mechanical cell lysis in that it doesn’t rely on any added chemicals or enzymes to promote cell disruption, thus making it a better option for large samples with tough cell walls (plant, fungi, bacterial and algal, etc.) where sensitivity might not be as big an issue and when unwanted additives could contaminate the lysate. Here’s how different homogenizers lyse cells:

 

1. Agitation, Stirring, Shearing and Impact

Mechanical homogenizers like blenders, mortars and pestles, bead mills, rotor-stator homogenizers and blade homogenizers use a blade, probe or beads to generate turbulent mixing that breaks apart cellular membranes. These types of homogenizers are especially useful because they can be customized in various ways (according to sample size and viscosity, processing time and agitation speed, to name but a few), making it easier to ensure that an appropriate amount of force is applied in the least disruptive way. This not only saves valuable time and money, it better safeguards cellular contents.

 

2. High-Pressure

Other types of homogenizers — high pressure homogenizers or HPHs — apply pressure to lyse cells. By squeezing cell suspensions through a narrow opening, HPHs effectively disrupt cellular bonds, leaving the intracellular contents exposed.

 

3. Ultrasonic Sound Waves 

Finally, some homogenizers make use of high frequency sound waves to create microbubbles within a cell suspension that expand, coalesce and then burst, causing cells to break apart. These types of homogenizers are known as ultrasonic homogenizers and are especially useful because the frequency and strength of the waves can be adjusted for both small and large samples, as well as a range of cell types. In addition, the amount of ultrasonic force can be amplified (or not) depending on the type of cellular barrier (i.e., more force can be applied when the sample is a plant cell and less when it is an animal one).

 

Ready to Learn More?

You need the right equipment to lyse cells. Different homogenizing methods offer different advantages and disadvantages. The key is matching the best process to your application and your available resources. We believe our homogenizers here at BEE International provide you with the most optimal solution because our patented Emulsifying Cell (EC) system provides you with options that a singular type of homogenizing system would not. With our machines you can combine and customize homogenizing forces so that your cell lysis processes are effective and profitable. Contact us to learn more.

You might also wish to download our free eBook, “7 Key Factors to Consider When Choosing A Cell Lysis Method,” for additional information.

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How Homogenization Improves Your Colloid Mixtures

Posted by Deb Shechter on Sep 16, 2019 11:10:57 AM

Colloid MixturesIf you had to write down a list of the qualities that all great products possess, what words would you choose? You’d probably start with functionality — a good product needs to serve a purpose. You’d also want it to taste or look or perform well. You might write down “value” and “sustainability.” And maybe you’d throw in “superior customer support.” While all of these characteristics accurately describe great products — no matter the industry — perhaps the most important one would be “reliability.” Great products are great only if they can be produced over and over again. For many industries (such as the food, pharmaceutical, chemical and biotech ones), great products depend on being mixed in the right way so that they appear and function the same way every time a new batch exits the manufacturing line. For colloidal suspensions, like those found in many food items and cosmetics, this means that they don’t separate or deteriorate while sitting on a shelf or in a drawer. Take a look at how you improve colloidal suspensions by using a high quality homogenizer:

 

Reduction of Particle Size

Put simply, homogenizers break apart substances. By disrupting a sample’s molecular bonds, homogenizers reduce particle size and facilitate the effective mixing of all the sample’s components. And clearly, smaller pieces make better mixtures. However, while most homogenizers utilize only one type of force to break apart and mix a sample (pressure, cavitation, turbulence, shear, or impact), our homogenizers here at BEE International are unique. Our equipment combines high pressure with all the other forces so that covalent bonds are less violently disrupted (thus, preserving other key elements), particle size is further reduced and components of a sample are more thoroughly mixed. Our proprietary homogenizing system has the added benefit of being completely customizable, allowing operators the ability to manage the duration, intensity and dominant force used at every stage of the mixing process.

 

Reduction of the Number of Passes

Furthermore, if a homogenizer does its job well, you don’t need to repeatedly pass product through its system for maximum results. Thus, fewer production passes means saved time and saved money, especially when used for large-scale manufacturing runs.

 

Preservation and Extension of Shelf Life

Another benefit of homogenization is its ability to help preserve products by creating a tighter distribution of very small particles. A tighter distribution of particles equates to more surface area on which chemical reactions can occur, with the result being better stability. Indeed, a tight distribution of particles helps mixtures stay coalesced for longer periods of time (i.e., better viscosity, consistency, texture, appearance and/or flavor), improves chemical reactions (i.e., better absorption and bioavailability) and eliminates volatile organic compounds (VOCs). When high pressure homogenization (HPH) is specifically used to mix colloidal suspensions, benefits are further compounded, as HPH acts as a preservation method, its intense pressure killing harmful microorganisms that could threaten the colloid suspension’s overall quality and length of its usefulness.

 

The BEE International Advantage

All industries need reliable products to be successful. If you’re in a business or research setting that requires you to mix together substances, you need equipment that ensures you the smallest particles and, therefore, the highest quality solutions and colloidal suspensions. Our patented Emulsifying Cell (EC) technology guarantees scale-up to production and reproduces reliable results. Every. Single. Time. Contact us to learn why manufacturers, researchers and lab managers around the world trust our equipment with their needs.

Please also download our free eBook, “Advantages of BEE Homogenizers for the Pharmaceutical Industry,” for more specific information about the benefit of using homogenizers within the pharmaceutical industry.

 

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3 Benefits of Ultrasonic Mixers

Posted by Deb Shechter on Aug 29, 2019 10:00:00 AM

ultrasonic mixers

All homogenizers work to disrupt molecular bonds so that two substances can be thoroughly mixed together. The force used to facilitate such mixtures varies; the most basic way to separate different types of homogenizers is by labeling them either mechanical (those using physical forces such as agitation, stirring, shearing and/or impact to break covalent bonds), high pressure (those using pressure) or ultrasonic (those using sonic sound waves and cavitation). There are drawbacks and advantages to each type of homogenizer depending on your application and resources. In this post, we consider the greatest benefits to using an ultrasonic mixer (also known as a sonicator) for your homogenizing needs.

 

Ultrasonic Mixers are Versatile

All homogenizers can effectively mix liquids, and some can mix samples of a solid with a liquid; ultrasonic mixers do both. When ultrasonic waves are applied to a liquid medium, a cycle of alternating high and low pressure eventually creates vacuum bubbles. These bubbles grow and merge together, ultimately reaching a size that collapses and sends a shock wave through the mixture (i.e., cavitation). The effect of these shock waves, as well as the vibrating tip of the ultrasonic mixer itself, disrupts surrounding covalent bonds of a sample, making an ultrasonic mixer a valuable piece of equipment capable of dissolving a wide range of materials (even gummy bears!).

 

Ultrasonic Mixers are Easily Controlled

Many variables impact how well a homogenizer does its job. These include size, concentration and temperature of the sample; the shape, speed, amplitude, intensity, pressure and duration of the “agitator;” and the temperature, viscosity and volume of the medium (as well as the type of container that holds it). While these factors can be difficult to adjust when using other types of homogenizers, they are easily manipulated when using an ultrasonic mixer. Indeed, technicians, scientists and manufacturers can easily adjust any or all of these elements in order to enable light or vigorous agitation (i.e., homogenizing) based on the need at hand.

 

Ultrasonic Mixers Have Fewer Parts

It might not seem like a huge advantage, but having fewer parts means ultrasonic mixers are less difficult to clean and less challenging to repair. Consisting of only a power source, a converter (which transforms electrical energy into mechanical motion) and a probe, a sonicator doesn’t have much to maintain. There is little frictional wear of parts and no intricate parts to clean.

 

Want to Learn More?

Ultrasonic mixers are just one type of homogenizer. If you need assistance choosing a homogenizer that meets the requirements of your own application(s) and makes the most of your own resources, contact our team at BEE International. Our proprietary and patented equipment addresses a wide range of functions at a reasonable range of costs. Not only do our homogenizers create a tight distribution of small particles, they always scale up and reproduce reliable results. Whether used inline or for batch processing, our homogenizers can be trusted to deliver the finest quality emulsions and dispersions available time after time.

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Homogenizer Machine: 3 Uses for the Pharmaceutical Industry

Posted by Deb Shechter on Aug 14, 2019 10:45:46 AM

homogenizer machineHomogenizer machines provide a number of benefits within a wide variety of industries. Whether used by a multi-million dollar dairy producer or a local boutique cosmetic company or countless types of businesses in between, homogenizers offer advantages that guarantee superior products no matter the application; when the stakes are especially high, they even help save lives. Just consider the pharmaceutical industry, where homogenizers are vital to the production of drugs tasked with maintaining or improving quality of life. In these instances, the value of a homogenizer machine can literally be the difference between life and death. Take a look at three ways homogenizers are used within the pharmaceutical industry:

 

To Maximize Stability

All homogenizers reduce particle size so that the elements of a substance can be more easily and more thoroughly mixed. In the pharmaceutical world, being able to break apart one part of a drug and completely meld it with another part is especially important because it increases the reliability of potency that good medicines should always deliver. Indeed, a stable (i.e., “invariable”) drug, when liquid, is often an emulsion in which two immiscible fluids have been forcibly combined in some way; they can also be dispersions of small, solid particles that have been mixed with a liquid. Shaking or stirring substances can produce brief periods of either type of mixture, but a homogenizer machine is the best way to effectuate an amalgamation that doesn’t eventually revert to the original states of the individual components. This is particularly significant as it allows manufacturers to guarantee the effectiveness of a drug’s impact while improving taste, appearance and viscosity along the way.

 

To Enhance Bioavailability

Stable drugs are able to provide greater bioavailabilty of their active ingredients. Their small particles allow a body to absorb a drug more quickly and more easily, thus enabling the drug to work more effectively overall.

 

To Extend Shelf Life

A homogenizer machine is vital for extending a product’s shelf life. As mentioned above, many energy sources can generate transitory fusion, but homogenizers so firmly reduce the size of and then bond components that any resulting pharmaceutical products they help produce last longer than those made via other mixing methods.

 

The BEE International Advantage

Homogenizer machines, especially high pressure ones like those designed and sold by our team here at BEE International, are vital to the production of a wide range of products, not least of which include those within the pharmaceutical industry. Our patented Emulsifying Cell (EC) technology incorporates shear, cavitation and impact to break down, mix and blend, helping you create quality drugs that last longer on the shelf and can be easily absorbed for maximum benefit in the least amount of time. If you are looking for a homogenizer machine that can transition you from concept, research and design to clinical trials, FDA approval and, finally, manufacturing, contact a member of our sales team. We can help you determine the right machine for your needs.

 

Please also download our free eBook, "Advantages of BEE Homogenizers for the Pharmaceutical Industry," for more information on the benefits of choosing one of our proprietary homogenizer machines.

 

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Ultrasonic Homogenizer 101: The Basics

Posted by Deb Shechter on Jul 31, 2019 12:43:50 PM

Ultrasonic HomogenizerHomogenizers come in a variety of shapes and sizes and operate under several different kinds of forces. The ultrasonic homogenizer is a specific type of homogenizer which uses ultrasonic waves and cavitation to force apart and reduce the size of particles (both liquid and solid) within a liquid substance.

 

The What

Also known as sonicators, ultrasonic homogenizers consist of three parts:

  1. A generator, which supplies energy.
  2. A converter, which converts and increases electrical energy into mechanical motion.
  3. A horn, probe or tip, which when placed into a liquid moves in a rapid fashion and causes bubbles to form. These bubbles expand and contract, breaking apart the surrounding particles (called cavitation).

 

The Why

Of course, the goal of homogenization is not only to break apart, but to mix, particles. And in this sense, ultrasonic homogenizers hold an advantage, as their stimulation of cavitation so effectively disrupts molecular bonds that the total particle surface area is greatly increased. This is because breaking apart particles creates more particles with more surfaces. And when there is a greater total surface area and a tighter distribution of particles, there is improved opportunity for particle agglomeration and overall improved stability.

 

Furthermore, ultrasonic homogenizers have fewer parts to maintain and to clean, and they can be customized according to specific amplitude and pressure ranges, making them great choices for scientists and manufacturers wanting complete control over the cavitation process.

 

The When

Ultrasonic homogenizers can be used to homogenize samples, lyse cells, reduce particle size, extract biological material, refine chemical processes and more, but only with liquid (or mostly liquid) samples. They are appropriate for application in both laboratory and industrial settings and are especially valuable when a sample can’t be stirred, doesn’t require grinding or cutting for processing and won’t be degraded by heat (as high temperatures often result with the rapid agitation of the sonicator tip).

 

The Who

As mentioned, ultrasonic homogenizers can be used in a wide variety of industries by all kinds of professionals. Life scientists can use them to facilitate sonoporation. Jewelers and opticians can use them to clean their merchandise. Food scientists, agriculturalists and chemists can use them to enhance their "soft goods" processing. Archaeologists can use them to uncover microfossils. Pharmaceutical researchers can use them to produce betters drugs. And these are just a few examples!

 

Want to Learn More?

Picking the right kind of homogenizer depends on the type of materials with which you work and what you want to accomplish with them. If you need help selecting the right homogenizer for your task, contact our team at BEE International.

 

Please feel free to also download our complimentary eBook, “7 Key Factors to Consider When Choosing a Cell Lysis Method,” for practical advice on enhancing your time, budget and skills with the right piece of equipment.

 

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What is a Polytron Homogenizer?

Posted by Deb Shechter on May 29, 2019 10:27:50 AM

Polytron HomogenizerIn the world of homogenizers, it’s a lot like Shakespeare’s Juliet said: “A rose by any other name would smell as sweet.” Depending on where you are and who you are, you might call a homogenizer a sonicator, a lysor, a bead mill, a high shear mixer, a disperser or a tissue tearor. You might even call a standard blender or whisk a homogenizer. Sometimes, people refer to all homogenizers by the brand name Polytron® (much like many call all tissues “Kleenex®”), and sometimes they specify the kind of homogenizer according to the type of force it supplies, like a mechanical, high-pressure or ultrasonic homogenizer. In the end, however, all these names refer to the same basic piece of equipment that is used by laboratories and in industrial processes to disrupt and blend the components of a product.  

 

But just because there are multiple ways to say “homogenizer,” it doesn’t mean each homogenizing application isn’t specific in some way. Indeed, the preferred way of referencing a homogenizer usually points to how it will be used, making it especially important for you to understand the differences in homogenizing applications.

 

For instance, in industry talk, a Polytron® homogenizer indicates a specific brand of immersion dispersers, which uses a rotating blade to dissolve solid particles in a liquid substance. Thus, “polytron homogenizer” is often used to reference a homogenizer being used with plant and animal matter in a lab setting. Similarly, “cell lysors” and “tissue tearors” are terms most likely used in biotech applications where it’s important that users maintain the cellular integrity of the products they’re manufacturing and/or studying.

 

The term “high shear mixer,” on the other hand, is more often used when discussing homogenizing processes for the food /beverage and chemical industries, where the mixing part of the homogenizing process is seen as being more emphasized than the disruption part (whether it’s true or not). In much the same way, you might talk about “bead mills” to indicate homogenizers used in industrial settings since they can accommodate the grinding of solid samples without a liquid.

 

Want to Learn More?

Choosing the right term to indicate each type of homogenizer is often confusing: Do you need a disperser? Do you call it a polytron homogenizer? And what about bead mills and all the other options? Add in the multiple ways in which each homogenizer can be applied, and you can quite easily become overwhelmed with possibilities! If you need assistance determining the right equipment for your needs, contact our team at BEE International. We offer a range of laboratory, pilot and industrial homogenizers that can effectively provide:  

 

Our proprietary and patented Cell Emulsifying System guarantees a customizable combination of homogenizing forces for optimal results and reduced costs. In addition, we offer stellar service, warranty support and preventative maintenance programs, benefits that enable you to maximize your time and resources and enhance the lives of the people you serve.

 

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How to Improve Oil Emulsification with a Homogenizer

Posted by Deb Shechter on Jan 31, 2019 11:00:00 AM

oil emulsification with homogenizersEmulsification is the process by which two naturally immiscible liquids are forcefully mixed together. Salad vinaigrettes, mayonnaise, butter, cold creams, lip balms and medicated ointments are all examples of emulsions. Depending on the ratio of oil to water, emulsions are typically categorized as either oil suspended in water (o/w) or water suspended in oil (w/o). Using the right emulsifying agent and the right kind of force, you can compel either type of mixture, effectively manufacturing many textile, plastic and paper products and improving the stability, bioavailability and viability for a variety of food, cosmetic and pharmaceutical ones (among others). Take a look at how a high pressure homogenizer can improve the oil emulsification process in particular, giving you better products in less time:

But First…The Difference Between an Emulsifier and a Homogenizer

Both emulsifiers and homogenizers forcefully mix many substances. But while an emulsifier only makes use of one type of mechanical force, a homogenizer makes use of many. At BEE International, our proprietary homogenizing system combines turbulent premixing with product progression through highly pressurized spaces, utilizing shear, cavitation and impact to break apart particles and uniformly mix and blend them. The result is a product with multiple benefits.

The Benefits of Using a Homogenizer in the Oil Emulsification Process

The benefits of using a homogenizer to create emulsified products are two-fold:

  1. It Reduces Particle Size

The high pressure and additional forces used by high pressure homogenizing systems (like those with our patented BEE International Emulsifying Cell technology) drastically reduce product particle size. Sub-micro particles have more surface area per particle, which means each has more opportunity to interact with another. This not only makes it easier for mixing agents to do their job (after all, they have a larger area on which to apply their “glue”), it also creates a final product with identical (i.e., homogenous) properties, improving the texture, consistency and appearance of many consumables, (especially important for those in the food and cosmetic markets) and increasing the bioavailability of drugs for the pharmaceutical industry.

  1. It Efficiently and Effectively Mixes Resistant Substances

The vigorous and multiple forces utilized by homogenizers make it harder for product particles to resist initial mixing and harder for them to separate afterwards. It also allows for large volume processing since homogenizers have greater capacities than traditional emulsifiers. The ability to create more stable products with longer shelf lives in shorter amounts of time with fewer passes saves time and money, valuable benefits for companies wanting to make the most of their resources.

Ready To Learn More?

The value of a high pressure homogenizer extends far beyond mere mixing of substances, making it the equipment of choice for companies wanting to maximize their processes while still achieving a superior meld. If you need assistance determining if or how homogenizers can improve your manufacturing turnover, as well as provide you with superior oil emulsifications, contact our team at BEE International. Our HPP homogenizers aid all types of businesses, including those in the food, pharmaceutical, chemical, biofuel and cosmetic industries and more. 

Feel free to also download our free eBook, "How to Achieve Efficient & Consistent Particle Size Reduction," for additional information about the value of smaller particle size within a manufacturing context.

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Three Reasons Cannabis Product Manufacturers Choose BEE International

Posted by Deb Shechter on Dec 27, 2018 11:30:00 AM

homogenizers for cannabis1At BEE International, we understand that quality products are reliable ones. Our high pressure homogenizers produce ingredients that make cannabis product manufacturing uniform and, thus, more effective. And in an industry where news of even one bad product or experience — whether due to poor quality or poor regulatory oversight — can give those opposed to legalized cannabis consumption the fuel needed to stoke their flames of dissent, it’s paramount that licensed cannabis manufacturers take the necessary steps to ensure that the products they deliver are of the highest quality. It’s not enough simply to get a product out there.

Cannabis manufacturers must verify both the consistency and the constancy of their products even if the market doesn’t officially demand that they do so. Take a look at three reasons cannabis product manufacturers choose to partner with BEE International:

Our Homogenizers Guarantee Efficacy

Our team at BEE International has developed cannabis-specific homogenizing processes into our equipment that effectively reduce cannabis particle size. By reducing particle size, the surface area of the cannabis increases, thereby also increasing the rates of dissolution and absorption (i.e., the bioavailabilty) of the active ingredient. This facilitates many advantages, from reducing the amount of active ingredient and time needed to produce optimal effect to stabilizing and extending shelf life for storage. These benefits translate into better products and more sales for you at the end of the day. 

Our Homogenizers Reduce Costs

Our specialized inline processes mean better results in less time. Our homogenizers establish reproducible results quickly, making it more efficient for you to validate product quality. By reducing your processing time, we can help reduce your manufacturing costs! And because our homogenizers are so good at minimizing particle size and increasing bioavailability, products made with our machines need less active ingredient to ensure superior performance. Thus, you can source less active ingredient and still produce the same great effects, saving you time and money. 

Our Homogenizers Create Stable and Uniform Particles for Quality Control

Regardless of end use, a cannabis product must be reliable and capable of being exactly reproduced. Its appearance and function must meet certain standards, with potency, appearance, consistency and even smell remaining uniform across manufacturing batches and through all moments of time. Our BEEI homogenizers help verify and maintain quality control by producing similarly sized ingredient particles that are uniform in appearance, smoother in texture and easier to mix together. We guarantee “a golden clear high performance oil” for quality products that are visually appealing and functional no matter the application. 

Want To Learn More?

Increased efficacy, lowered costs and guaranteed quality are just a few of the benefits BEE International homogenizers offer. Download our free eBook below to better understand how our proprietary processes can strengthen your cannabis products, securing you valuable market share.

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What Are Homogenizing Agents & How Do They Improve the Homogenization Process?

Posted by Deb Shechter on Dec 17, 2018 12:10:59 PM

homogenizing agentsFor most people, “homogenization” and “homogenizing agents” aren’t words that just roll off the tongue. But for us here at BEE International, talking about them comes as easily as discussing our favorite TV show or the day’s weather. So, if you’ve ever wondered what “homogenized milk” meant or how your face cream was made or why some peanut butter doesn’t have to be stirred, we’d love to share with you the facts about high pressure homogenization and homogenizing agents. Consider the following:

An Overview of the Homogenization Process

Homogenization is the process of combining two substances by breaking them into uniform pieces and mixing them together evenly. Homogenization facilitates many laboratory and manufacturing processes, such as those in the pharmaceutical, biotech, chemical, cosmetic and food industries. Not only does homogenization change the physical characteristics of materials, making it easier for scientists and manufacturers to work with raw components, it also helps ensure product quality, maintain long-term storage of materials and isolate certain particles when necessary. All of these things are necessary for superior performance among a variety of products. Homogenization makes our milk taste good and keeps our peanut butter from separating into a lump of peanut paste and a pool of oil. It keeps our lotions thick, yet spreadable, and our medicines effective.

But what if certain materials resist homogenization attempts by mechanical equipment alone? What if they need something more to help break them apart and realign their parts equally? In these cases, homogenizing agents are used.

What are Homogenizing Agents?

Homogenizing agents are resin-based mixtures which are usually added at the beginning of a homogenization cycle. When heated to certain temperatures, they turn “sticky” and help to moisten and soften the surfaces of the substances being melded together. 

How Do They Improve the Homogenization Process?

Because of their tackiness, homogenizing agents make it easier for some substances to blend and distribute their particles evenly. They also encourage filler acceptance. And by helping to shorten the time it takes to blend materials regardless of their “molecular weight, viscosity or polarity,” homogenizing agents save energy and other valuable resources.

In scientific and research settings, efficient homogenization can do more than just save time, though. It can also save lives. The right homogenizer and the right homogenizing agents can reduce the number of passes it takes to get viable results, ensuring that all steps in the testing cycle are consistent and go as smoothly and quickly as possible.

In more industrial settings, the right homogenizers and homogenizing agents ensure that applications are customized according to overall purposes, whether that be securing product stability; guaranteeing sterility; improving color, texture, taste and nutritional value; or simply maintaining cost effectiveness. 

Need More Info?

If you need help selecting the right homogenizer for your homogenization process, contact us today. Our high pressure homogenizers are customized to suit your own unique needs with multiple mechanical forces that create thoroughly mixed products.

And for additional information, you might also like to download our FREE eBook: "How to Achieve Efficient & Consistent Particle Size Reduction." In it, we show how equipment that reduces particle size saves you money by extending shelf life and strengthening biophysical properties. 

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Six Tips for Ensuring Safety When Using Your High-Pressure Homogenizer

Posted by Deb Shechter on Jul 12, 2018 10:30:00 AM

high pressure homogenizerSafety first. It’s a phrase you hear fairly often, and although it may seem unnecessary to repeat, it’s especially important when working with large machines or those with many parts. When not used correctly, these machines can not only fail to produce an optimal product but also cause injury. 

Homogenizers fit into this category, so we’re offering the following tips on how to use yours and the samples it produces both safely and effectively:

1. Wear the appropriate protective equipment.

As with any such machine, these elements are designed to keep the user safe from moving parts and any hazardous chemicals. Whether it’s gloves, eye goggles or even ear plugs, investing in these accessories can keep you from damaging any part of your body, especially your eyes and ears. Some high-pressure homogenizers can reach 85 dBA and potentially cause ear damage.

2. Follow operating instructions and regulations.

There are safety laws and guidelines produced by unions and the government for a reason. These rules are designed to keep you safe while ensuring the machine you’re using is working as it was designed to do. To make sure you always have your high-pressure homogenizer’s instruction manual when you need it, keep it with the machine, and store a copy with your other important documents.

3. Use only the parts that came with your high-pressure homogenizer.

The parts that make up your high-pressure homogenizer are designed to work together and should not be substituted with another accessory or attachment. Failure to follow this rule may cause your product to work at a decreased level or even break, often voiding your warranty.

4. Avoid contact with the rotating shaft and homogenizing head.

Contact with either of these sharp parts can cause injury, so make sure you always switch the machine off before cleaning it or changing screens. Be especially careful when handling your high-pressure homogenizer after it has been contaminated with dangerous samples.

5. Let only trained operators handle your high-pressure homogenizer.

When installing or operating your homogenizer or simply doing maintenance on it, have only those trained to do so perform the task. Improper handling can cause both machine malfunction and minor injury to the handler.

6. Follow common electrical precautions.

Again, these rules are in place for a reason, and failing to follow such rules may result in electrocution or shock.

BEE International: Putting Safety First

At BEE International, our line of equipment is suitable for virtually every industry and can work in just about any environment, letting you focus on other important projects. Plus, we work with you to make sure you understand the appropriate safety precautions and provide training for all our products. To learn more, please contact us today.New Call-to-action