5 Facts About Homogenizers for the Biotech Industry

Posted by Deb Shechter on Aug 30, 2017 11:30:00 AM

Image of DNA strand against colour background-285750-edited.jpegHomogenization in the Biotech industry is used for many applications, including cell disruption, particle size reduction, micro and nano emulsions, and dispersions. In this growing industry, homogenizers are used to effectively rupture yeast, bacteria, E. coli, fungi cells, and more.

Keep reading to discover five interesting facts about homogenizers for the biotech industry.

  • The first homogenizer was invented in 1899 by Auguste Gaulin, a French inventor. This early homogenizer was developed to aid the milk industry, and broke milk’s fat globules into smaller, more uniform sizes in order to resist separation.
  • Modern homogenization involves a two step process: particles are first pushed through tubes or pores to reduce their size, and they are then subjected to high pressures to further reduce their particle size.
  • In the Biotech industry, homogenization is more commonly referred to as micronization or cell fractionation.
  • Cell fractionation is a procedure for rupturing cells and creating separation and suspension of cell components in a given medium (usually water or an organic solvent).
  • Cell fractionation involves three steps: Extraction, Homogenization, and Centrifugation. During the extraction phase, molecules, tissues, or cells are isolated and suspended in an isotonic solution. During the homogenization step, the cell is ruptured to create a smaller particle size.

At BEE International, we offer a number of industrial-grade homogenizers that use state of the art technology to help with emulsification, dispersion, and grinding of particles. In addition to our revolutionary technology, we also offer homogenizers that utilize a constant processing pressure. This allows our equipment to produce consistent rates of pressure and eliminates the risk of any contamination.

At BEE International, our homogenizers improve results in the biotech industry, allowing this important industry to create more effective medications, chemicals, vaccines, and more. Please contact us today to learn more about our equipment and how we can assist with your next big project. We look forward to working with you.

For more information on homogenizers and cell lysis methods, download our FREE eBook:

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Biotechnology, Homogenization