Homogenization – also known as micronization or simply particle size reduction, is a process that is utilized in a number of growing industries: pharmaceutical, biotech, cosmetic, and food are just a few of the industries that use this innovative technique. Homogenization represents just one way of reducing a given particle’s size, and within the field of homogenization, there are numerous ways to achieve that task. Ultrasonic homogenizers and high pressure homogenizers are two pieces of machinery that are often looked at by those interested in particle size reduction. However, before selecting the right homogenizer for the task at hand, it is important to understand how each of these two types of homogenizers work. Continue reading to learn more about ultrasonic homogenizers and how they change the homogenization process.
Ultrasonic homogenizers are also known as sonicators, and are often used for the homogenization and lysis of smaller samples that do not require traditional grinding or rotor-stator cutting techniques for processing, such as laboratory samples. Ultrasonic homogenizers utilize ultrasonic probes to get the job done. These probes, which come in a variety of sizes, are often made of titanium or another chemical resistant material, and allow for a variety of sample volumes to be processed.
Ultrasonic homogenizers are very efficient for the reduction of both soft and hard particles, and since there are few moving parts involved, there is less frictional wear and cleaning time involved. Ultrasonic homogenizers also allow for a great deal of control over the parameters influencing the homogenization process. However, ultrasonic homogenizers can generate a great deal of heat, which can be harmful to samples that are temperature-sensitive.
High Pressure Homogenizers
High Pressure Homogenizers, like Ultrasonic Homogenizers, are also adept at reducing the particle size of a number of materials. Similar to ultrasonic homogenizers, high pressure homogenizers also use the force of cavitation; however, other forces, such as shear and impact, are also used. This allows for a gentle (but very effective) process of particle size reduction.
BEE International offers a number of high quality homogenizers to meet the needs of virtually every industry. Benefits include:
- Gentle and effective particle size reduction
- Better results in fewer passes
- Scalable results
- Suitable for cell disruption, particle size reduction, nano & micro emulsions and dispersions
- Easy cleaning and maintenance
- Lifetime training for new employees and students
For more information on cell lysis methods and how to choose the right one, download our FREE eBook: