What Is Emulsification and How Is It Used in Cannabis Production?

Posted by Deb Shechter on Aug 26, 2020 9:15:00 AM

Bee International helps cannabis producers with emulsification to create a superior productThe legal cannabis industry is a multibillion dollar enterprise that rests largely on the quality of the cannabis plant’s active components. Called cannabinoids, these chemical compounds — when effectively harvested and processed — are capable of bonding with receptors in our bodies and have the potential to produce anti-inflammatory, analgesic, euphoric and/or calming effects. Indeed, cannabinoids have been used by humans, both clinically and recreationally, for thousands of years, suggesting they are safe to consume with many beneficial properties.

But just because humans have a history of safely using cannabis products, it doesn’t mean that all cannabis products are created equal. Changes to federal and state laws have decriminalized cannabis use and relaxed criminal mandates in many areas of the country, allowing more and more players to enter the CBD and cannabis market. The result: a plethora of products but few standards. Yes, most states regulate the manufacture of cannabis products, but many lack even minimum requirements for potency, safety and/or testing; consumers are simply at the mercy of manufacturers, hoping they actually get what they pay for.

To better guarantee the quality and effectiveness of their products, reputable manufacturers work to create their own production processes that both sustain and maximize cannabinoid stability and bioavailability and deliver reliable results — in this case, medicines and products that are capable of provoking specific physiological effect(s) — each and every time. They do that by emulsifying the cannabis during production. Here’s how it works:

What Is Emulsification?

Emulsification is the mixing together of two or more substances that wouldn’t normally be able to combine. A chef vigorously whisking oil into vinegar to make a dressing is an example momentarily of a mix, but within seconds separation occurs. Emulsification adds an emulsifying agent, something that successfully binds the oil and water phase together without separation.

Cannabis manufacturers also use emulsification to ensure that the cannabinoids they extract from cannabis plants are able to be incorporated into viable products — drinks, creams, edibles and more that taste, look and/or smell good and that deliver the same results with each production run. The stability of these products, part of which is determined by the length of time the components do not separate, extends shelf life and expiration date.

How Are Homogenizers Used in Cannabis Production?

The process starts with the harvesting of the cannabis plant. From there, a manufacturer must extract the cannabinoids, basically a sticky syrup that is then refined, purified and distilled (or separated) from compounds that aren’t needed, such as terpenes, flavonoids and other contaminants. It is this resulting substance — an oily, bitter isolate that naturally repels water — that necessitates the emulsification process. At this point, the cannabinoid isolate is exposed to mixing equipment that uses one or more forces to break apart the chemical bonds of the cannabinoids and reduce the size of their particles.

Homogenization is the ideal mixing method. It is an in-line process, which means that all particles undergo the same mixing forces and there is less variation in the results. This eliminates “hot spots “in the end product. Homogenization is also an efficient mixing process, which means less time to produce a better effect.

Why BEE International Homogenizers Are the Best at Emulsifying

Typical emulsifiers use only one type of force, but a BEE International homogenizer uses multiple forces (turbulence, cavitation, shear and impact) to break apart and reduce particles. This creates smaller particles, maximizing the surface area of the cannabinoids.

BEE International homogenizers are versatile, with the ability to deliver a gentle mix to the most intense mixing process with up to 45,000 PSI. The intensity breaks product particles into the smallest size, down to nanometers. Smaller particles make it easier for their particles to completely mix, stay mixed with the aid of an emulsifier and deliver a product that is shelf stable and ready to be used. Smaller particles also increase potency and bioavailability up to 75%.

Only BEE International homogenizers have an option to eliminate the need for pre-mixing. This increases the efficiency and ease of the manufacturing process with less equipment and fewer manufacturing phases.

To learn more about the benefits of our patented Emulsifying Cell (EC) technology, as well as our proprietary systems, please contact us. We can help you choose equipment that guarantees safe and effective products, enabling you to stand superior to the competition and offer the most benefits to consumers.

 

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Everything You Need to Know About the Homogenization of Cells

Posted by Deb Shechter on Jan 31, 2020 12:13:15 PM

homogenization of cellsThe homogenization of cells refers to the process by which all components of a biological sample are made equal. By breaking down cell membranes/walls, it allows for the thorough mixing of a sample’s cellular contents. The result: a sample that has a consistent and uniform molecular make-up. Here’s everything you need to know about cell homogenization:

 

The Homogenization Process

The homogenization of cells is basically a cell lysis technique meant to release the intercellular contents of cells so that they can be better accessed, maintained and/or mixed. There are other ways to disrupt (or lyse) cells, such as cryopulverization, nitrogen decompression and more, but the most popular method is homogenization. Homogenization uses one or more types of mechanical force to break apart and mix the components of a sample. When used with biological materials, cell homogenization allows scientists to isolate and study the contents of cells and manufacturers to make better products.

 

Why You Should Homogenize Cells

There are many reasons to choose cell homogenization over other cell lysis methods, the most significant being that different types of cells require different disruption techniques. For instance, some cells are fragile and need a more sensitive means for cell lysis lest the entire cell be destroyed during the process. Some cells have tough outer matrices or walls, warranting a more extreme cell lysis force in order for valuable intercellular contents to be reached. Some cells need enzymes or other reagents added to them to facilitate lysis, and in other cases, the cell lysis procedure itself either creates or relies on a certain temperature that can comprise or otherwise negate optimal results. The considerations are varied and wide-ranging with everything from the cost of the equipment, the size of the sample and stability, reproducibility and scaling problems to even physical space constraints (to accommodate the size of the equipment) also affecting the selection of one cell lysis method over another.

 

The Value of High Pressure Homogenization of Cells

Here at BEE International, we believe that homogenization — specifically, high pressure homogenization — affords the best value for many scientists and manufacturers alike. Our high pressure homogenizers offer a customizable approach to the cell homogenization process, with our patented Emulsifying Cell (EC) technology allowing you to control the type and duration of the force(s) used according to multiple cell types. Indeed, our proprietary homogenizing system can rupture cell walls and membranes without damaging any other crucial cell components, making our equipment effective, efficient and extremely competitive. If you would like to learn more about the homogenization of cells and how high pressure homogenizers can improve your productivity, as well as strengthen the quality of the products you test and create, please contact us. We believe cell homogenization offers countless benefits when used as a part of many research and manufacturing processes.

 

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How to Pick the Right Homogenizer for Colloidal Suspensions

Posted by Deb Shechter on Dec 26, 2019 12:34:22 PM

colloidal suspensionsWhen choosing a homogenizer for a particular application, it’s important to first understand the differences among solutions, colloids and suspensions. Each is a type of mixture, and a mixture is one of the end results of the homogenization process. Thus, picking the right homogenizer directly influences the quality of the mixture you create.

 

What are the Difference Among Solutions, Colloids and Suspensions?

A solution is a homogenous mixture where one substance (the solute) is completed dissolved into another (the solvent). Solutions can be a combination of any two phases (solid, liquid or gas), but they always result in a single, continuous one. A colloid, on the other hand, is a heterogenous mixture with particles that are bigger (1-1,000 nm) than those of a solution (<1 nm) but smaller than those in a suspension; because of their size, particles in a colloid do not allow light to pass through the mixture, instead scattering it back outward in a process known as the Tyndall Effect. They are not so big, however, that they aren’t able to stay fully mixed, with components unable to be separated by filtration, time or rest. Last, but not least, a suspension is also a heterogenous mixture. Its particles are bigger than those found in both solutions and colloids; they are so large, in fact, that gravity is able to pull them down and settle them at the bottom of the mixture when it’s not being actively mixed.

 

What Should You Look for in a Homogenizer for Colloidal Suspensions

Colloidal mills are a type of “rotor-stator” or “high shearmixer specifically designed to work with colloid suspensions. As such, their function is to reduce particle size so that two substances can be mixed together more easily. The shearing force of the spinning rotor effectively disrupts molecular bonds within a sample and reduces particle size. They are most often used for mixing together two liquids, a solid with a liquid and/or highly viscous materials. However, colloid mills can’t be run continuously because they consume large amounts of energy, which could potentially contaminate any resulting product mixture. Thus, instead of assuming that a colloid mill is the only option for use with colloidal suspensions, users should consider a homogenizer that affirms the following questions:

Does it Reduce Particle Size? ✔️

Does it Reduce the Number of Passes? ✔️

Does it Help Preserve the Product? ✔️

 

Unlike a colloidal mill, a homogenizer is better able to reduce particle size so that resulting mixtures are much more consistent and uniform. Indeed, we believe our high pressure homogenizers here at BEE International are the best option for colloidal suspensions because they utilize a proprietary combination of high pressure, shear, cavitation, turbulence and impact force to break down and blend samples without the violence and possible degradation of product that can be associated with a singular shear force. Furthermore, our machines can be customized to control the duration, intensity and dominant force used at every stage of the mixing process, making it less likely that multiple passes will be needed to get a desired result. This saves you time and money.

Finally, all homogenizers help preserve products since they facilitate a tight distribution of particles; a tighter distribution of particles means there is more stability, allowing components of a sample to stay bound for longer periods of time and, thus, engendering the improved viscosity, consistency, texture, appearance and flavor (when applicable), as well as the bioavailability, of the products being made. High pressure homogenizers like ours even kill harmful microbes that frequently jeopardize the colloid suspension’s shelf life and quality.

 

Want to Learn More?

Picking a homogenizer to use with colloidal suspensions is best determined by its ability to confer the most benefits. In addition to generating well mixed samples, a BEE International high pressure homogenizer offers tighter particle distribution, improved stability, better preservation and increased manufacturing productivity when compared to other types of homogenizers and mixers. Contact us to learn more.

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What is the Purpose of Homogenization?

Posted by Deb Shechter on Nov 21, 2019 1:00:00 PM

purpose of homogenizationHomogenization is the process by which a sample is broken into identical parts so that removing one portion of it does not disrupt and still accurately reflects the remaining sample’s molecular composition. In many instances, it is also used to thoroughly mix together naturally immiscible substances; when a sample is reduced to tiny, uniform pieces, it is easier for manufacturers and scientists to combine it with another sample, creating many of the products used across a wide variety of industries.

Here’s a brief overview of the purpose of homogenization:

 

To Reduce Particle Size

First and foremost, the purpose of homogenization is to reduce the size of the particles making up a sample. In simple terms, it’s a bit like taking a boulder and smashing it into gravel, except, in this case, the gravel pieces would be all the same size and shape. During homogenization, many samples can be reduced to nanometer-sized particles. This makes it easier for manufacturers to produce things like adhesives, resins, paints and creams/lotions and guarantee that they work.

 

To Lyse Cells

For the molecular and cellular biology fields, one of the most common purposes of homogenization is to breach the cell wall and/or membrane and expose the intracellular contents of cells. This is necessary when scientists need to make biological samples for further study, experimentation and research.

 

To Kill Pathogens

One the the added benefits of many homogenization techniques is the destruction of pathogens within a sample. There are several kinds of homogenizers (mechanical, high pressure and ultrasonic), each using one or more specific types of force. As a by-product of the processing method each force facilitates, many homogenizers render samples with varying levels of sterility. For instance, high pressure homogenizers can effectively kill microorganisms in food samples. Other homogenizers that produce high levels of heat (most mechanical homogenizers) can kill various pathogens, as well, but the accompanying heat frequently degrades the overall sample. Thus, it’s important to pick the right kind of homogenizing equipment if product sterility is a requisite goal.

 

To Facilitate Stable Emulsions and Dispersions

Finally, the purpose of most homogenizers is to mix substances well. Reducing the size of the particles in a substance allows it to more readily and easily combine with the particles of another substance. It also allows all of the particles to remain mixed for a longer period of time. This is especially important for products that need to be consistent in appearance, taste, texture, viscosity and/or nutritional value for the length of their shelf lives, like cosmetics, food and beverage items and pharmaceuticals.

 

The BEE International Advantage

Homogenization offers a host of benefits, and we here at BEE International believe our high pressure homogenizers are the best choice, offering advantages that would otherwise necessitate the purchase of multiple types of equipment instead of just one! Our patented Emulsifying Cell (EC) technology, along with our proprietary combination of multiple homogenizing forces, mean our homogenizers have the ability to create more stable products with longer shelf lives in shorter amounts of time with fewer passes than our competition. Please contact us to capitalize on all the purposes of homogenization or if you're interested in the particle size reduction side of homogenization, download our free eBook now:

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The Pros and Cons of High Shear Homogenizers

Posted by Deb Shechter on Nov 4, 2019 9:22:00 AM

high shear homogenizersThere are many types of homogenizers. From basic blenders to refrigerator-sized ultrasonic equipment, different homogenizers work in and for a variety of different applications. This means choosing the right homogenizer for a specific job is a critical one. Pick the wrong homogenizer and you risk less than optimal results, some of which can cost you valuable time and money, as well as jeopardize the integrity of the products you create and/or the health of the people you serve.

 

In this blog, we take a look at high shear homogenizers. Also known as rotor-stator homogenizers, high shear mixers are one specific kind of mechanical homogenizer.
Mechanical homogenizers, as opposed to high pressure or ultrasonic ones, use a physical force to break apart a substance; in this case, a rapidly spinning rotor draws a sample into a stationary outer sheath (called a “stator”), where it is then pushed through many small openings and broken into small pieces. The rotor’s pull and the stator’s expulsion creates a significant force that consequently shears the sample apart, permitting it to be mixed more effectively in subsequent applications as needed. But while high shear mixers can be applied in a variety of ways with several associated benefits, a few potential issues do exist. Take a look at the pros and cons of the high shear homogenizer:

 

The Pros of High Shear Homogenizers

High shear homogenizers operate at a high velocity to pull, push and break apart a sample. Thus, they generate substantially smaller particles than some other kinds of homogenizers and are an especially good option for the following applications:

    1. Particle Size Reduction/Sub-Micron Homogenization

    2. Soft Tissue Homogenization

    3. Emulsification

    4. Cell Disruption and/or Isolation

    5. Organelle Extraction

 

Furthermore, high shear homogenizers often generate favorable results in a relatively short amount of time with minimal residual heat produced. Many models can be customized according to sample volume, rotor speed, processing time and energy input, with the option of using different probes to afford different effects being one of their most appealing and useful qualities.

 

The Cons of High Shear Homogenizers

On the other hand, high shear mixers are not very efficient with tough tissue samples, lysols or foams. And not all come with the probe(s) you will need for your specific task(s). Indeed, the fact that high shear homogenizers use probes at all means they are not as well-suited to processing large amounts of multiple samples at the same time since they have to be swapped out and cleaned between runs. In addition, because pieces of a sample must fit within the confines of the probe and its accompanying rotor and stator parts in order to be homogenized, some samples might need to be pre-processed, broken apart just so that they can fit into the homogenizer at all! Of course, should this circumstance arise, time-effective processing would obviously be negated. Finally, although high shear homogenizers don’t give off an excessive amount of heat, particularly temperature-sensitive samples might require that you add a cooling method to your homogenizing processes, thereby extending your processing time and costs.

 

The BEE International Difference

Picking the right homogenizer can be a tricky endeavor. If you need assistance matching your needs with the right piece of equipment, please contact a member of our team here at BEE International. We offer a variety of high-quality homogenizers featuring our proprietary and patented Emulsyfying Cell (EC) technology which, along with our combination of customizable forces (think: high shear meets sonication meets impact!) , guarantees you the most reliable and effective results no matter the application.

 

Feel free to also download our complimentary eBook, “7 Key Factors to Consider When Choosing a Cell Lysis Method,” for additional tips on choosing a homogenizer that meets your needs and maximizes your resources.

 

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How Homogenization Improves Your Colloid Mixtures

Posted by Deb Shechter on Sep 16, 2019 11:10:57 AM

Colloid MixturesIf you had to write down a list of the qualities that all great products possess, what words would you choose? You’d probably start with functionality — a good product needs to serve a purpose. You’d also want it to taste or look or perform well. You might write down “value” and “sustainability.” And maybe you’d throw in “superior customer support.” While all of these characteristics accurately describe great products — no matter the industry — perhaps the most important one would be “reliability.” Great products are great only if they can be produced over and over again. For many industries (such as the food, pharmaceutical, chemical and biotech ones), great products depend on being mixed in the right way so that they appear and function the same way every time a new batch exits the manufacturing line. For colloidal suspensions, like those found in many food items and cosmetics, this means that they don’t separate or deteriorate while sitting on a shelf or in a drawer. Take a look at how you improve colloidal suspensions by using a high quality homogenizer:

 

Reduction of Particle Size

Put simply, homogenizers break apart substances. By disrupting a sample’s molecular bonds, homogenizers reduce particle size and facilitate the effective mixing of all the sample’s components. And clearly, smaller pieces make better mixtures. However, while most homogenizers utilize only one type of force to break apart and mix a sample (pressure, cavitation, turbulence, shear, or impact), our homogenizers here at BEE International are unique. Our equipment combines high pressure with all the other forces so that covalent bonds are less violently disrupted (thus, preserving other key elements), particle size is further reduced and components of a sample are more thoroughly mixed. Our proprietary homogenizing system has the added benefit of being completely customizable, allowing operators the ability to manage the duration, intensity and dominant force used at every stage of the mixing process.

 

Reduction of the Number of Passes

Furthermore, if a homogenizer does its job well, you don’t need to repeatedly pass product through its system for maximum results. Thus, fewer production passes means saved time and saved money, especially when used for large-scale manufacturing runs.

 

Preservation and Extension of Shelf Life

Another benefit of homogenization is its ability to help preserve products by creating a tighter distribution of very small particles. A tighter distribution of particles equates to more surface area on which chemical reactions can occur, with the result being better stability. Indeed, a tight distribution of particles helps mixtures stay coalesced for longer periods of time (i.e., better viscosity, consistency, texture, appearance and/or flavor), improves chemical reactions (i.e., better absorption and bioavailability) and eliminates volatile organic compounds (VOCs). When high pressure homogenization (HPH) is specifically used to mix colloidal suspensions, benefits are further compounded, as HPH acts as a preservation method, its intense pressure killing harmful microorganisms that could threaten the colloid suspension’s overall quality and length of its usefulness.

 

The BEE International Advantage

All industries need reliable products to be successful. If you’re in a business or research setting that requires you to mix together substances, you need equipment that ensures you the smallest particles and, therefore, the highest quality solutions and colloidal suspensions. Our patented Emulsifying Cell (EC) technology guarantees scale-up to production and reproduces reliable results. Every. Single. Time. Contact us to learn why manufacturers, researchers and lab managers around the world trust our equipment with their needs.

Please also download our free eBook, “Advantages of BEE Homogenizers for the Pharmaceutical Industry,” for more specific information about the benefit of using homogenizers within the pharmaceutical industry.

 

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3 Benefits of Ultrasonic Mixers

Posted by Deb Shechter on Aug 29, 2019 10:00:00 AM

ultrasonic mixers

All homogenizers work to disrupt molecular bonds so that two substances can be thoroughly mixed together. The force used to facilitate such mixtures varies; the most basic way to separate different types of homogenizers is by labeling them either mechanical (those using physical forces such as agitation, stirring, shearing and/or impact to break covalent bonds), high pressure (those using pressure) or ultrasonic (those using sonic sound waves and cavitation). There are drawbacks and advantages to each type of homogenizer depending on your application and resources. In this post, we consider the greatest benefits to using an ultrasonic mixer (also known as a sonicator) for your homogenizing needs.

 

Ultrasonic Mixers are Versatile

All homogenizers can effectively mix liquids, and some can mix samples of a solid with a liquid; ultrasonic mixers do both. When ultrasonic waves are applied to a liquid medium, a cycle of alternating high and low pressure eventually creates vacuum bubbles. These bubbles grow and merge together, ultimately reaching a size that collapses and sends a shock wave through the mixture (i.e., cavitation). The effect of these shock waves, as well as the vibrating tip of the ultrasonic mixer itself, disrupts surrounding covalent bonds of a sample, making an ultrasonic mixer a valuable piece of equipment capable of dissolving a wide range of materials (even gummy bears!).

 

Ultrasonic Mixers are Easily Controlled

Many variables impact how well a homogenizer does its job. These include size, concentration and temperature of the sample; the shape, speed, amplitude, intensity, pressure and duration of the “agitator;” and the temperature, viscosity and volume of the medium (as well as the type of container that holds it). While these factors can be difficult to adjust when using other types of homogenizers, they are easily manipulated when using an ultrasonic mixer. Indeed, technicians, scientists and manufacturers can easily adjust any or all of these elements in order to enable light or vigorous agitation (i.e., homogenizing) based on the need at hand.

 

Ultrasonic Mixers Have Fewer Parts

It might not seem like a huge advantage, but having fewer parts means ultrasonic mixers are less difficult to clean and less challenging to repair. Consisting of only a power source, a converter (which transforms electrical energy into mechanical motion) and a probe, a sonicator doesn’t have much to maintain. There is little frictional wear of parts and no intricate parts to clean.

 

Want to Learn More?

Ultrasonic mixers are just one type of homogenizer. If you need assistance choosing a homogenizer that meets the requirements of your own application(s) and makes the most of your own resources, contact our team at BEE International. Our proprietary and patented equipment addresses a wide range of functions at a reasonable range of costs. Not only do our homogenizers create a tight distribution of small particles, they always scale up and reproduce reliable results. Whether used inline or for batch processing, our homogenizers can be trusted to deliver the finest quality emulsions and dispersions available time after time.

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Ultrasonic Homogenizer 101: The Basics

Posted by Deb Shechter on Jul 31, 2019 12:43:50 PM

Ultrasonic HomogenizerHomogenizers come in a variety of shapes and sizes and operate under several different kinds of forces. The ultrasonic homogenizer is a specific type of homogenizer which uses ultrasonic waves and cavitation to force apart and reduce the size of particles (both liquid and solid) within a liquid substance.

 

The What

Also known as sonicators, ultrasonic homogenizers consist of three parts:

  1. A generator, which supplies energy.
  2. A converter, which converts and increases electrical energy into mechanical motion.
  3. A horn, probe or tip, which when placed into a liquid moves in a rapid fashion and causes bubbles to form. These bubbles expand and contract, breaking apart the surrounding particles (called cavitation).

 

The Why

Of course, the goal of homogenization is not only to break apart, but to mix, particles. And in this sense, ultrasonic homogenizers hold an advantage, as their stimulation of cavitation so effectively disrupts molecular bonds that the total particle surface area is greatly increased. This is because breaking apart particles creates more particles with more surfaces. And when there is a greater total surface area and a tighter distribution of particles, there is improved opportunity for particle agglomeration and overall improved stability.

 

Furthermore, ultrasonic homogenizers have fewer parts to maintain and to clean, and they can be customized according to specific amplitude and pressure ranges, making them great choices for scientists and manufacturers wanting complete control over the cavitation process.

 

The When

Ultrasonic homogenizers can be used to homogenize samples, lyse cells, reduce particle size, extract biological material, refine chemical processes and more, but only with liquid (or mostly liquid) samples. They are appropriate for application in both laboratory and industrial settings and are especially valuable when a sample can’t be stirred, doesn’t require grinding or cutting for processing and won’t be degraded by heat (as high temperatures often result with the rapid agitation of the sonicator tip).

 

The Who

As mentioned, ultrasonic homogenizers can be used in a wide variety of industries by all kinds of professionals. Life scientists can use them to facilitate sonoporation. Jewelers and opticians can use them to clean their merchandise. Food scientists, agriculturalists and chemists can use them to enhance their "soft goods" processing. Archaeologists can use them to uncover microfossils. Pharmaceutical researchers can use them to produce betters drugs. And these are just a few examples!

 

Want to Learn More?

Picking the right kind of homogenizer depends on the type of materials with which you work and what you want to accomplish with them. If you need help selecting the right homogenizer for your task, contact our team at BEE International.

 

Please feel free to also download our complimentary eBook, “7 Key Factors to Consider When Choosing a Cell Lysis Method,” for practical advice on enhancing your time, budget and skills with the right piece of equipment.

 

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What Does a Homogenizer Do?

Posted by David Shechter on Jul 16, 2019 9:25:31 AM

What Does a Homogenizer Do?There are many types of homogenizers, from the basic kitchen blender and handheld, laboratory dounce homogenizer that use mechanical force to break apart and blend food or other “ingredients” to the numerous kinds of large, industrial homogenizers that rely on pressure to effectively disrupt and mix microscopic components of a sample. There are even ultrasonic homogenizers that use cavitation to produce similar results. But just what does a homogenizer do, you might wonder? How does it work?

 

While the specifics of how a homogenizer does what it does changes based on the composition of the materials on hand and the proposed intent of the product to be made, the basic premise of what it does is always the same. Thus, despite the fact that there are dozens of different types of homogenizers, all of them basically do the same thing: apply force(s) in order to separate the parts of one substance and thoroughly mix them with the parts of another.

 

Why Use Homogenizers?

Homogenizers are used to completely mix a solid, liquid or gas into another substance, but they also offer several other key benefits and, thus, are invaluable across numerous industrial, chemical, biotechnological and food manufacturing processes. Specifically, in addition to the aforementioned blending purpose, businesses use homogenizers to reduce the particle size of various types of substances; facilitate the elimination of pathogens in food products (also known as pasteurization); improve the stability, appearance and texture of chemical compounds (including things such as paint, makeup and medications); increase the bioavailability of pharmaceutical products; extend product shelf life; maintain consistent levels of quality; and reduce manufacturing costs.

 

In short, homogenizers enable companies to guarantee efficacy and efficiency no matter their application. Indeed, some homogenizers achieve results by agitating and stirring. Some do it by crushing and grinding. Others push suspensions through narrow passages, and some use pressure and impact. But regardless of the type of force used, all homogenizers aim to mix together two naturally immiscible substances so that any number of the above benefits can occur.

 

Ready to Learn More?

Homogenizers do a lot of different things, making them useful tools that foster a myriad of advantages across several separate industries. If you need assistance determining the type of homogenizer best suited to your needs, contact our team at BEE International. Our homogenizers combine high pressure with turbulence, cavitation, impact and shear forces, which, when coupled with our patented Emulsifying Cell (EC) technology, serves to improve manufacturing and laboratory processes and saves you valuable time and money.

 

And for additional information, feel free to download our complimentary eBook, “How to Achieve Efficient & Consistent Particle Size Reduction." In it, we detail how our proprietary in-line processing technology maximizes particle size reduction in fewer passes and helps you maintain cost-effective manufacturing practices.

 

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When is the Right Time to Purchase an Industrial Homogenizer?

Posted by David Shechter on Jun 12, 2019 9:00:00 AM

Industrial HomogenizerIn manufacturing terms, bigger is often better, especially if you’re talking about the equipment that companies need to process the products they sell. Indeed, profitability frequently depends on a company’s ability to meet consumer demand while simultaneously maintaining quality and safeguarding costs. Many accomplish this by utilizing large capacity processing equipment to render bigger outputs in less time. By increasing product volume, decreasing manufacturing duration and maintaining the integrity and reliability of both via automated (not manual) processes, companies in all types of industries can generate bigger financial gains.

 

For those industries tasked with creating homogenized products, large scale equipment can facilitate better micronization, better mixing and better scalability (i.e., better overall results). If you’ve ever struggled to meet the demands of your customers or to verify the accuracy, efficacy, constancy and consistency of your products, then investing in an industrial homogenizer will likely solve a lot of your problems. Here’s how you’ll know it’s the right time to purchase an industrial homogenizer:

 

You Have High Product Demand

Industrial homogenizers are created specifically for bulk processing. Whereas laboratory homogenizers are perfectly capable of (and generally preferred for) handling small batch loads, industrial homogenizers can accommodate large quantities of materials, making it easier for companies to process a lot of product in less time. If you’ve moved past the initial research and development stage and have a final product to mass produce, it’s the right time to buy an industrial homogenizer.

 

You Need Flexibility for Processing

An industrial homogenizer is usually more versatile than a laboratory homogenizer, with advanced options available for tailoring processing functions according to individual need. At BEE International, our industrial homogenizers incorporate our patented Emulsifying Cell (EC) technology, a linear process that guarantees scalability of results each and every run. Our machines also include proprietary software, the “most advanced, reliable, and versatile intensifier technology on the market” and an automation system that allows for continuous operation, advanced data collection and integration with plant controls, generating countless opportunities for customization.

  

You Want To Minimize Costs

Bigger machines can cost more and warrant more maintenance. However, our DeBEE 4000 industrial homogenizer model comes equipped with hydraulically-driven vertical intensifier pumps that effectively lower maintenance costs and a “unique CIP position [that enables] flow through the high pressure cylinder for faster and more thorough cleaning.” Both of these features help keep our machines running smoothly and cleanly. Oftentimes, smaller homogenizing systems become overstressed trying to accommodate the processing of an unrealistic load. This not only wears out the machine’s mechanics, it requires more labor, more maintenance and probably more repair, all factors that accumulate more expense in the long run. A BEE International industrial homogenizer can mitigate that problem.

 

You Must Verify Safety Compliance

Manufacturing plants are required to adhere to certain sanitary and safety guidelines. Thus, most industrial homogenizers support compliance with FDA, CGMP and 3-A standards. Our BEE International industrial homogenizers offer this feature, as well as additional ones meant to make cleaning machine parts easier and more effective so that you can adhere to industry standards with minimal disruption to the production process. You should purchase an industrial homogenizer if you are required to verify any trade and/or government guidelines.

 

Want to Learn More?

Homogenizers are essential expenses for companies needing to homogenize and/or reduce the size of the particles in their product(s). Industrial homogenizers, in particular, can help large companies meet manufacturing demand, validate quality and ensure product stability and performance. All our equipment comes with a two year warranty to further protect your investment, your time and the trust of the people you serve. Contact us to learn more.

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