BEE International Blog

How High Pressure Homogenizers Benefit Dispersions

Posted by Deb Shechter on Aug 29, 2016 12:30:00 PM

high pressure homogenizersDispersions occur when particles of one (solid) substance are scattered throughout another (liquid) substance. The solid particles are sometimes referred to as agglomerates or aggregates. Dispersions can be further categorized into solutions (homogeneous mixtures) or suspensions (heterogeneous mixtures). A colloid is a third type of dispersion that is somewhere in between a solution and a suspension.

The IUPAC definition of a colloidal dispersion is: A system in which particles of colloidal size of any nature (e.g. solid, liquid or gas) are dispersed in a continuous phase of a different composition (or state). The name “dispersed phase” for the particles should be used only if they have essentially the properties of a bulk phase of the same composition. A dispersion can be defined as a colloid if particle size is between 0.001 micrometer and 1 micrometer.

High Pressure Homogenizers in Manufacturing

Dispersions are used to produce thousands of products across many industries like the pharmaceutical industry (e.g. antacids or antioxidants), the food industry (e.g. ketchup or sports drinks) and the chemical industry (e.g. inks and dyes). Although dispersions are a very useful application, the production of dispersions is not without its challenges. Problems can include instability, agglomeration (clumping) and equipment clogging, inability to reduce particle size to meet requirements, and contamination caused by wear on the mixing equipment.

DeBEE High Pressure Homogenizers for your Dispersion Products

BEE International systems are designed to produce consistent dispersions with a tight distribution of smaller particles and to reduce agglomeration by consistently distributing surfactants. Our proprietary technology applies force with no grinding or mixing action. The energy is applied fluid-on-fluid, offering an exceptionally long life cycle of all parts.

Our flexible technology also addresses products with unique processing challenges such as pastes requiring fine particles, agglomeration difficulties, hard materials and products requiring a longer shelf life.

Visit our website to read more about the particular benefits of using a high pressure homogenizer in the pharmaceutical, chemical, biotech and food industries.

BENEFITS OF DEBEE HIGH PRESSURE HOMOGENIZATION

Product

Improved product quality

Longer shelf life

Increased bioavailability

Improved sensory characteristics like taste, texture and color

Improved nutritional value

Manufacturing

More efficient productivity due to fewer passes

Lower manufacturing costs due to fewer passes

Less clogging, maintenance and downtime


Are you in the pharmaceutical industry? Download our FREE eBook: “Advantages of BEE Homogenizers for the Pharmaceutical Industry” and discover how to improve your dispersion products and more!

New Call-to-action

Topics: High Pressure, Homogenizer

How Does a High Pressure Homogenizer Work for Optimal Cell Lysis & Particle Size Reduction?

Posted by Deb Shechter on Aug 26, 2016 12:30:00 PM

high pressure homogenizerHigh pressure homogenization is a mechanical process that works to reduce particle size or to lyse cells. Essentially, a liquid is forced at high pressure through a very narrow nozzle. The higher the amount of energy applied during the homogenization process, the smaller the particle size or the more complete the cell lysis.

Below, we’ll discuss the forces used to apply this energy; as well as the differences that set DeBEE high pressure homogenizers apart from the competition.

Our unique BEE International technology begins right at the product intake, which can be laminar and gentle, or turbulent for premixing. As the liquid enters the homogenizer nozzle, there is a sharp drop in pressure, causing cavitation. Cavitation occurs when a rapid pressure change causes “liquid-free zones” or cavities in a liquid. As these cavities collapse, shock waves are generated throughout the liquid, which causes the particles to break apart.

The liquid continues on into an absorption chamber which contains alternating small and large orifices, which creates turbulence and causes fluid-on-fluid impact and shear. As a result of the application of these forces (cavitation, turbulence, impact and shear), the liquid that now flows out of the homogenizer has a much smaller particle size than before.

The DeBEE Difference

The above process describes a basic high pressure homogenizer set up, but our DeBEE high pressure homogenizers offer several additional benefits:

  • Process Intensity and Duration: Our high pressure homogenizers can be configured with a reverse flow setup, where the high velocity liquid jet is made to reverse on itself and to exit near the nozzle, thus causing even more impact and fluid-on-fluid shear. The duration of the process can be controlled by the length and internal configuration of the absorption chamber. Process intensity is adjustable from 2000 - 45000 psi / 150 - 3100 bar.
  • Constant Pressure:  A constant processing pressure leads to a more uniform particle size. Our unique High Pressure Pumping System uses several hydraulically driven intensifier pumps for a constant, uninterrupted processing pressure. This pumping system also eliminates the possibility of contamination. Read more about it here.
  • Modular Technology: BEE International’s proprietary technology allows independent control of pressure, flow, cavitation, impact, shear, and process duration. This allows you to optimize cell lysis or particle size reduction and obtain the best possible results for your product.

Contact us today to request a quote or a demonstration and experience the DeBEE difference! For more information about particle size reduction and how to achieve efficient and consistent results, download our FREE eBook:

New Call-to-action

Topics: Particle Size Reduction, High Pressure, Cell Lysis

Chemical Methods of Cell Disruption

Posted by David Shechter on Aug 24, 2016 12:30:00 PM

cell disruptionCell disruption, or cell lysis, is achieved when the cell wall or membrane is ruptured, releasing the contents of the cell. Cell disruption is the first step in many biotechnology applications. This sensitive process needs to be controlled as much as possible; and choosing the correct cell lysis method is essential for preserving the desired intracellular contents.

Cell disruption can be achieved in several ways, including mechanical, enzymatic or chemical lysis. Read on to learn more about chemical methods of cell disruption:

The very simplest form of chemical cell lysis is osmotic lysis. Here, cells are suspended in a hypotonic extracellular environment (often a dilute sucrose solution). This causes the cells to take on water, swell and subsequently burst. Osmotic lysis does not occur in plant cells due to their sturdy cell walls. Organic solvents like alcohols, ether or chloroform can disrupt cells by permeating the cell walls and membranes. These solvents are often used (in combination with shearing forces) with plant cells.

EDTA (ethylenediaminetetraacetic acid) is a chelating agent which can be used to disrupt gram negative microorganisms, since it chelates the cations, leaving holes in the cell walls.

Surfactants (commonly called detergents) disrupt the distinct interface between hydrophobic and hydrophilic systems.  Detergents are used in cell lysis buffers and they help to solubilize membrane proteins and lipids thereby causing the cell to lyse and release its contents. Widely used detergents include Triton and sodium dodecyl sulfate (SDS).

Chaotropic agents, such as urea and guanidine, are also used for cell lysis. They are capable of bringing some hydrophobic compounds into aqueous solutions. They do this by disrupting the structure of water and making it a less hydrophilic environment, and weakening the hydrophobic interactions among solute molecules.

Disadvantages of Chemical Methods of Cell Disruption:

A major drawback in using chemical methods of cell disruption in manufacturing is the cost. Using small amounts of chemicals and enzymes in the R&D laboratory is acceptable; but the cost of using the large volumes required for large-scale production is often not feasible.

Harsh chemicals and detergents can often damage or destroy the contents of the cell if used incorrectly. Lastly, using large volumes of potentially hazardous chemicals creates significant health and safety risks.

The Benefits of Mechanical Cell Disruption with High Pressure Homogenization:

Our high pressure homogenizing technology at BEE International allows you to gently rupture cells without damaging the valuable intracellular materials. You are able to control the pressure, allowing for rupture of a variety of cell types. No harsh chemicals are introduced into the process, and all results are 100% scalable to manufacturing.

For more information on cell disruption, download our FREE eBook: 7 Key Factors to Consider When Choosing a Cell Lysis Method or contact us today!

New Call-to-action

Topics: Cell Disruption, Cell Lysis

Hammer Mills vs. High Pressure Homogenizers for Particle Size Reduction

Posted by David Shechter on Aug 17, 2016 12:30:00 PM

high pressure homogenization for particle size reductionWhat is a Hammer Mill and How Does It Work?

A hammer mill is a machine designed to crush material into smaller pieces by way of repeated blows from small hammers. Hammer mills work on the principle that most materials will crush, grind, shatter or pulverize upon impact.

Material is fed into the mill grinding chamber through the feed chute. The material is repeatedly struck by hammers which are attached to a rotating shaft inside the mill chamber. The material is crushed and particle size is reduced as the particles are struck by the hammers, and also as they collide with the chamber walls and with each other. The clearance space between the mill chamber and the hammers also contributes to particle size reduction. The discharge opening of the mill is covered by a screen which allows only particles that have reached the desired size to pass through.

For a quick visual, watch this video: https://www.youtube.com/watch?v=NSUbcndrCnI

What Are the Downsides of Using a Hammer Mill?

The first major disadvantage is that almost every component of a hammer mill is subject to rigorous wear-and-tear. Along with cost, this leads to more frequent maintenance, more down-time and even the possibility of product contamination. Hammer mills can also be energy inefficient, especially if they are old or not properly maintained. Hammer mills also generate heat, especially at when run at high speeds, which may be undesirable for certain applications.

With regards to particle size, there is great variability when using a hammer mill. This is because particle size is determined only by screen-hole size; meaning that any sized particle under a certain size can pass through. Lastly, hammer mills often produce a lot of fine dust, and can also be very noisy.

DeBEE High Pressure Homogenizers: Leaders in Efficient and Uniform Particle Size Reduction

Homogenizers are the most efficient fluid processing equipment for particle size reduction. Unlike a hammer mill that uses only one mechanical force (impact), BEE International’s patented technology utilizes ALL available mechanical forces. Our proprietary homogenizing cell technology essentially drives the fluid at ultra high pressure through a small nozzle, causing cavitation. The product becomes a high velocity jet stream and flows through an absorption cell. This absorption cell contains alternating small and large orifices that create turbulence and cause fluid-on-fluid impact and shear. Process intensity is adjustable from 2,000 - 45,000 psi / 150 - 3100 bar.

All of this is done with no grinding or mixing action. The energy is applied fluid-on-fluid, offering minimal wear on all homogenizer components. For more on this and information on our High Pressure Pumping System, click here.

BEE International’s unique, modular technology allows these forces to be individually fine-tuned, allowing you to produce the best possible results for your product. With DeBEE high pressure homogenizers, you are guaranteed a tight distribution of smaller particles, and maximum particle size reduction in fewer passes.

Contact us to discuss your particular homogenizing needs. For more information about particle size reduction and how to achieve efficient and consistent results, download our FREE eBook: 

New Call-to-action

Topics: Particle Size Reduction

Dounce Homogenization vs. High Pressure Homogenization

Posted by Tal Shechter on Aug 16, 2016 12:30:00 PM

high pressure homogenizationWhat is a Dounce Homogenizer?

Invented by Alexander Dounce, a Dounce Homogenizer (also known as a tissue grinder or a “Douncer”) is a small, handheld mortar and pestle made of glass. It lyses tissue and cells using shear stress as the sample is squeezed through the small space between the mortar (or tube) and pestle. See an example of a Dounce Homogenizer here.

The sample is placed into the tube and the pestle is then pressed down and lifted up repeatedly. The shear can be controlled, to a very limited degree, using different sized pestles. The larger the diameter of the pestle, the smaller the clearance space between the pestle and tube, and the greater the shear.

Pros and Cons of a Dounce Homogenizer

The primary benefit of using a Dounce Homogenizer is that it allows for tissue and cells to be lysed whilst leaving the smaller organelles (like the cell nuclei) intact. They can be useful in enzyme applications where heat must be avoided. They are also relatively inexpensive, and easy to use and clean.

However, the limitations of a Dounce Homogenizer far outweigh the benefits. This manual process is extremely time consuming. Plus it is limited to small volumes and results are inconsistent and not scalable. Although Douncers are inexpensive, they are not a cost effective option in the long run; as they are very fragile and tend to break easily.

DeBee High Pressure Homogenizers: A Better Way to Lyse Cells

Cell lysis (or cell rupture / cell disruption) is a process required for research and manufacturing across many industries, including biotechnology.

At BEE International, our technology utilizes an in-line process that customizes forces like shear, cavitation and impact to break apart particles in a controlled fashion. These forces are adjustable, allowing the user to optimize cell rupture according to the specific cell type. E. coli, yeast, bacteria, mammalian tissue, insects and fungi cells can each be ruptured with the most efficient process for the highest recovery rates.

Our DeBee High Pressure Homogenizers yield a high cell rupture for a wide variety of cells, but without damage to cell tissue or other valuable intracellular materials. As always with DeBee High Pressure Laboratory Homogenizers, all laboratory developments are 100% scalable to manufacturing. 

Sound too good to be true?

Try us and see for yourself! Contact us for a free, confidential sample testing. We’ll run your product on one of our DeBee High Pressure Homogenizers and return it to you, along with a detailed evaluation and analysis report.  

For more information about cell lysis methods and factors you should consider when choosing the right one for you, download our FREE eBook:

New Call-to-action

Topics: Homogenization

7 Questions to Ask Before Choosing a Homogenizer

Posted by Deb Shechter on Aug 12, 2016 12:30:00 PM

homogenizer1. Is this homogenizer a good fit for my product?

Particle size reduction, cell lysis, high pressure pasteurization, emulsions, dispersions” – these are our application buzzwords here at BEE International. We utilize all available mechanical forces (turbulence, shear, impact, cavitation and process intensity) to achieve optimum results for a variety of applications & products. If you’re in the market for a homogenizer, DeBEE high pressure homogenizers are the logical choice.

BEE International offers extensive application support, whether you need to create a new product, or improve an existing one. Click here to learn more about our free, confidential sample testing at our Massachusetts laboratory.

2. Is it high quality?

All DeBEE high pressure homogenizers use cutting edge technology to bring you consistent and reliable results. Our homogenizers use modular and flexible patented homogenizing cell core technology that allows you to configure the homogenizing cell set up to meet your application needs and processing goals.

Our proprietary High Pressure Pumping System is designed to produce a constant 45,000 PSI of operating pressure while eliminating product contamination. All DeBEE homogenizers employ our proprietary intensifier pumps for heavy duty, long life cycle, and leak free service.

3. How will it benefit my organization?

DeBEE high pressure homogenizers provide a great return on your investment. They increase manufacturing efficiency by ensuring maximum particle size reduction in fewer passes; leading to reduced production costs and waste.

4. Is it from a reputable company?

BEE International is a respected company with representation worldwide. We have been in operation for 22 years and have homogenizers in commercial and academic laboratories across the globe.

5. Is it easy to clean and maintain?

Yes! Our laboratory high pressure homogenizers are all easy to use, clean and maintain. We provide instructional videos for your convenience.  

We understand rigorous industry standards and customer requirements; therefore our pilot plant and industrial homogenizers are all Clean In Place (CIP). Contact us to schedule a professional service for your unit or inquire about our annual Preventive Maintenance Agreements.

6. Will I receive training for my staff?

BEE International Applications and Service Group will gladly install your new homogenizer in the field, and provide training. We also offer training for any new staff members or operators further down the line. Contact us here to enquire about our training programs and to schedule your training session.

7. What about technical support?

BEE International offers extensive and free technical support via telephone or email. Our helpful technical support staff are quick to respond and will resolve your query in record time.

We know that choosing a homogenizer isn’t always easy so we are here to help! Contact us today for more information and assistance in getting the right homogenizer for your applications.

To learn more about particle size reduction and how to get efficient and consistent results, download our FREE eBook: 

New Call-to-action

Topics: Homogenizer

Nano DeBEE vs. Mini DeBEE High Pressure Homogenizers

Posted by David Shechter on Aug 11, 2016 12:30:00 PM

Nano DeBEE Laboratory Homogenizer:unspecified.jpeg

This top-of-the-range bench top homogenizer is ideal for laboratory experimentation for a broad range of applications including cell disruption, particle size reduction, nano/micro emulsions and dispersions. Experimentation options include parallel flow, reverse flow, and variable process times and operating pressures. We also supply a variety of processing nozzles and reactors.

The Nano DeBEE Laboratory Homogenizer is designed to produce a tighter distribution of results, with maximum particle size reduction and increased product stability.

This sleek and quiet unit is a must-have in any laboratory, whether it be pharmaceutical, biotech, cosmetic, chemical or food. It is 100% scalable to manufacturing, and comes with your choice of two configurations:

  • Cell lysis Nano DeBEE, or
  • Maximum Experimentation Nano DeBEE

Mini DeBEE Laboratory Homogenizer:unspecified_1.jpeg

This robust bench top homogenizer is essential for any R&D laboratory. With the highest process intensity in the industry, this unit gives you free reign to experiment and obtain the precise particle or droplet size that you need.

The trusted Mini DeBEE Laboratory Homogenizer is used in pharmaceutical, biotech, cosmetic, chemical and food laboratories all over the world. It has PLC electronic control and monitoring for ease of operation, and customizable options are available for your every application.

The Nano DeBEE and Mini DeBEE are both easy to use, clean, and maintain. Remember, we offer demonstration videos and lifetime training for all of your new employees and students. Click here for installation, training, and technical support information.  

The following table provides a side-by-side comparison of specifications for the Nano DeBEE and Mini DeBEE Laboratory Homogenizers:

 

Nano DeBEE


Mini DeBEE

Maximum pressure

Cell lysis

Maximum Experimentation

Continuously adjustable

0 to 45,000 PSI /

3,100 bar

30,000 PSI / 2000 bar

45,000 PSI /

3100 bar

Adjustable back pressure

YES

YES

0 to 5,000 PSI / 350 bar

Flow rate

70 or 120ml/min

Continuous up to 250ml/min

Minimum sample size

15ml

30 ml standard

DeBEE patented modular homogenizing cell

YES

YES

Heat exchanger for product cooling

YES

YES

Weight

45 lbs (20 Kg.)

350 lbs / 160 kg

Dimensions

29"W x 6"D x 13"H

(73 W x 15 D x 33 H cm)

55" W X 20" D X 30" H  

(140 X 51 X 76 cm) 

Power Supply

110V or 220V power supply, single phase*

3-phase, 50/60 Hz, 220 VAC - 5.5HP (4 kW)

* Separate power unit on wheels available: 16"W x 16"D x 26"H (41 W x 41 D x 68 H cm) - 88 lbs (40 Kg.)

Contact us at BEE International for more information about our products and how they can help you. 

Looking for a homogenizer for your pharmaceutical applications? Both the Nano & Mini DeBEE are perfect for laboratory research & development. If you’re considering a BEE International homogenizer, download our FREE eBook to see why BEE homogenizers are perfectly suited for the pharmaceutical industry:

New Call-to-action

Topics: Homogenization, Homogenizer

Particle Size Reduction 101: Homogenization, Dispersions & Emulsions

Posted by Tal Shechter on Aug 10, 2016 12:30:00 PM

particle size reductionThe term “particle size reduction” means exactly that - the process of reducing average particle size in a given substance.  

Homogenization is one kind of particle size reduction. It is a process that uses mechanical force to break down particles or droplets in a liquid into smaller and more uniform sizes. The result of homogenization is a dispersion, where fine particles of one substance are scattered throughout another substance.

Dispersions can be further classified by the sizes of these scattered particles:

  1. Solution: a homogenous mixture with tiny particles of a molecular size (e.g. sugar in water).
  2. Suspension: a heterogeneous mixture with large particles that will often settle out on standing or can be filtered out (e.g. sand in water).
  3. Colloid: a mixture that is somewhere in between a solution and a suspension. An emulsion is a type of colloid and is a mixture of two immiscible (unmixable) liquids. The first liquid forms tiny particles scattered throughout the second liquid. Oil and water, for example, will form an opaque suspension when mixed, but will separate on standing (1).

Particle size reduction through homogenization has countless applications in many industries including food, pharmaceutical, biotechnology, cosmetic and more. A common example of a homogenized liquid is milk. In the days before homogenization, milk naturally separated and a layer of fatty cream would rise to the top; leaving what was essentially skim milk below. Homogenization is used to break up the fat globules into smaller droplets so that they remain suspended in the milk, creating an even, homogenous mixture (2).

BEE International: Your Partner in Particle Size Reduction

BEE International is the supplier of high pressure homogenizers. The BEEI difference lies in the fact that we synergistically combine and fine-tune all available mechanical forces (including turbulence, cavitation, shear, impact and process intensity) in order to produce the best possible product for you. We produce a tight distribution of small, uniform particles every time. Depending on your product, benefits include a longer shelf life, increased bioavailability, improved sensory characteristics, and greater productivity and lower manufacturing costs due to fewer passes.  

Our laboratory, pilot and industrial homogenizers all produce reliable and consistent particle size reduction. Contact us and we would be excited to develop a customized solution just right for you.

Want to know more about particle size reduction? Download our FREE eBook: How to Achieve Efficient & Consistent Particle Size Reduction

New Call-to-action

Topics: Particle Size Reduction, Homogenization, Dispersions, Emulsions

The Best Lab Equipment for Pharmaceutical Companies

Posted by David Shechter on Aug 9, 2016 12:30:00 PM

Pharmaceutical CompaniesWhen we hear the term ‘pharmaceutical company’, let’s face it- many of us think of vast wealth. And although this is true for a small few, more of them struggle to churn out products that can compete with the big names. To get any of these products to market, pharmaceutical companies must wade through drug development and, if lucky, the manufacturing process. Keep reading for some of the most important pieces of equipment that will aid with these processes.

Autoclave

Functional sterilizers are indispensable to pharmaceutical companies and, really, every single existing laboratory. Of the available sterilizers, the autoclave is one of the more effective at decontaminating lab materials through its use of heat and high pressure. (1)

Capsule Sealing Machine

Necessary for any pharmaceutical company that manufactures drug tablets is the machine that fills and seals each capsule. Capsule sealing machines work to first fill and then seal the capsules, which contributes to creation of a functional drug product. (2)

High Pressure Homogenizer

Of both higher cost and value than the other items on this list is the high pressure homogenizer. Homogenization forces a fluid through a narrow field at high pressure to reduce particle size, which can create products like emulsions, suspensions, dispersions, and lipids for use in an array of pharmaceutical products. (3)

Tablet Coating Pan

Coating pans help with the process of tablet synthesis by applying a coating of choice to the tablet core. Importantly, the process is incredibly intricate in its use of different coating types and ingredient ratios, but can be easily accomplished with either a perforated or conventional coating pan. (4)

Vessel (AKA Batch Reactor)

The vessel serves as a controlled environment within which chemical reactions can take place. Important to pharmaceutical companies is its ability to process small sample sizes, which are frequently used in the R&D stage of drug development. (5)

BEE International: Reliable Pharmaceutical Processing Equipment

As you begin your search for some of the above-listed items, you will be bombarded with corporations selling the equipment you want. To ensure that you select high-quality and reliable products, begin your search with us! BEE International products have innovative technology that offers unique benefits for producing nano/micro emulsions and dispersions, lipids and suspensions for vaccines, targeted drug delivery, inhalants, time release, anesthetics and antibiotics.

Our pharmaceutical process equipment produces unprecedented results by allowing the formulations expert to optimize the mixing process, which allows for better-suited product characteristics. We are also familiar with the long road traveled by pharmaceutical companies, from an idea to R&D, clinical trials, FDA approval and manufacturing.

Learn more about BEEI and the processing equipment we offer by contacting us today. 

For more information about our homogenizers and how they can be used in the pharmaceutical industry, download our FREE eBook:

New Call-to-action

Topics: Pharmaceutical

The Advantages of Homogenization in Food Production

Posted by David Shechter on Aug 8, 2016 12:30:00 PM

homogenization in food productionIn Maslow’s hierarchy of needs, the fundamental physical need is physiological. Metabolic requirements, air, and water supplement the internal functioning, while clothing and shelter fulfill the necessary external protection from the elements. And although humans can make the clothing and shelter, food is the only internal requirement that can be artificially produced. Homogenization is increasingly used as a method of food production because of its various advantages over other methods. Keep reading to learn about some of the higher-impact advantages of homogenization and how your food production process can benefit.

Improves Food Processing Outcomes

A consumer’s decision to purchase one food brand over another is largely based on its consistency, taste, and appearance. The processing method that dictates these factors should, therefore, be carefully considered, with homogenization being most common. In 2013, tomato juice was shown to have improved consistency and viscosity because of high pressure homogenization, which suspended particles during processing. (1) The simple ability to improve food processing outcomes can really elevate a product above competitors to increased company sales.

Highly Effective as a Food Preservation Method

Like with food outcomes, high pressure homogenizers are also incredibly effective as a food preservation method. In fact, the method continues to increase in popularity over traditional heat treatment for its high level of function. The reason for this is that although both high pressure and heat can kill harmful microorganisms, heat exposure kills some of the food’s naturally-occurring nutrients- while high pressure homogenization leaves them untouched and ready for consumption.

Extends Shelf Life

Related to food preservation in terms of chemical stability is shelf life, or the ability of a food to stay fresh before consumption. The intensive pressure applied by a high pressure homogenizer causes most foods to attain more stable chemical structures; this allows for a longer period of freshness than would otherwise be possible, especially compared with foods comprised of larger particles.

BEE International: High Quality Particle Size Reduction Equipment

A food’s ability to have its intended effect can be attributed to a wide variety of factors, in particular the size of its particles and consistency in particle size. Every food manufacturer should therefore consider each as food production processes are established. The first step in synthesizing a food product with high bioavailability is purchasing equipment that will achieve consistent particle size distribution. One such example is the high pressure homogenizer by BEE International Technology. Their products are trusted by researchers and lab managers around the world for key benefits, such as production of nano/micro emulsions, dispersions, and suspensions; importantly, this equipment can achieve consistent particle sizes at or below 100 nm, a key benefit for any product coming from the food industry.

Learn more about how BEE International can aid your particle size reduction process by contacting us today. 

For more information on cell lysis methods and how to choose the right one, download our FREE eBook:

New Call-to-action

Topics: Food Processing, Homogenization

Ask Us Anything

Categories

Industries

Pharmaceuticals

Biotechnology

Chemical

Foods

Cosmetics

Fuel

Applications

 Particle Size Reduction

Micro/Nano Emulsions

Dispersions

Cell Rupture

Lipids

Abrasive and Viscous Materials