Homogenization – also known as cell fractionation or micronization – is the process of dividing particles into microscopic sizes, ranging anywhere from 0.5 microns to 2 microns, depending on the application. Homogenizers play an important role in the pharmaceutical industry, and are commonly used for dispersions, emulsions, particle size reduction, and cell rupture.
Keep reading to discover the advantages of homogenizers for pharmaceutical products in the ever-growing pharmaceutical industry.
1. Reduced Particle Size
Effective homogenization results in a smaller particle size and more even distribution of active ingredients. For topical pharmaceutical products, such as medicated creams, lotions, and ointments, this allows for those medications to absorb more rapidly into the skin. A reduction in particle size increases the surface area of critical (and often expensive) active ingredients, which allows for an even dispersion of the active ingredients in the product, which increases efficacy of pharmaceutical products and lowers cost as well.
2. Increased Stability of Pharmaceutical Products
High-quality homogenizers have the ability to reduce the particle size of critical active ingredients, which in some cases can help improve the stability of these otherwise unstable active ingredients. Some critical active ingredients used in the pharmaceutical industry are solid at room temperature, and only moderately soluble in water or organic solvents. Effective homogenization can reduce these otherwise difficult to work with active ingredients into a small enough size that they have increased solubility in these mediums, many of which can work further to increase the shelf life and stability of the active ingredients.
3. Increased Reliability in Manufacturing Settings
Pion's BEE brand offers a number of first-class homogenizers that can meet the needs of manufacturers in the pharmaceutical industry. Our industrial homogenizers are designed for cGMP manufacturing, and offer reliability suitable for all industries, including those with a 24/7 operating schedule. Our proprietary software offers touch screen guided operation, data collection, security, on-line maintenance schedules and alarms, and configurable recipes and capacities.
Pion's BEE brand industrial homogenizers and high pressure homogenizers are manufacturing pharmaceutical, chemical, life sciences, food, cosmetic products, and more. Contact us today to discuss the benefits our homogenizers can bring to manufacturing your company’s products.
