High pressure homogenizer use is widespread, occurring internationally in labs that reduce particle size, lyse cells, create emulsions, and more. Yet considering the impressive number of people who come in contact with a homogenizer, there is a scarcity of literature that details safety tips and/or warnings. Of course, training in safe operation of a laboratory device before using it is necessary. However, particularly after using the same device for a long period of time, a safety refresher can be invaluable. Here we present some key hazards and tips for handling a homogenizer safely, so that it may be used effectively.
Hazard #1: Contact with rotating shaft and/or homogenizing head
The rotating shaft is key to a homogenizer’s particle size reduction ability, and the homogenizing head houses the narrow gap that a sample is forced through. Yet contact with either component can cause injury. To avoid contact and related injury, always switch off the machine before cleaning or changing screens.
Hazard #2: Manual handling of the homogenizing head
The homogenizing head can be raised or lowered to provide customization to a sample. Yet improper handling can cause both machine malfunction and minor injury to the handler. Simple training in safe equipment adjustment should be sufficient for the user to avoid injuring himself/herself and the homogenizer.
Hazard #3: Noise that can reach unsafe levels
This tip may or may not be relevant, depending on the homogenizer model and manufacturer. Some homogenizers can reach 85 dBA, and potentially cause ear damage. To avoid this hazard, a user can wear ear defenders when operating the equipment and/or decrease the period of exposure.
Hazard #4: Electrical equipment
Simple training in the use of both homogenizers and their associated plug-ins/electrical equipment should be sufficient to avoid electrocution or shock.
Pion: The Homogenizer Advantage
As you work to determine which high-pressure homogenizer brand and model will be best suited for your laboratory, begin your search with Pion's BEE brand technology. We are globally recognized among laboratory managers and researchers for our high quality products and excellent customer support. Cell lysis and particle size reduction are two of a variety of applications for Pion's BEE brand homogenizers; nano/micro emulsions, lipids, suspensions, and dispersions are also easily achievable.
Importantly, Pion's homogenizers can achieve consistent particle sizes at or below 100 nm, a key benefit for products that require smaller droplet sizes. Additionally, the homogenizer processes can be controlled to suit your product, which will allow you to customize to your cell type. And finally, the equipment is easy to use, produces higher yield in less time, and achieves results that are reproducible and scalable.
Learn more about how Pion's BEE brand homogenizers can improve your experimentation by contacting us today.
