resources
Very Thin PAMPA Membranes Indicate Higher Antipyrene Permeability but are Fragile and Contain Leaky Water Pores
Poster
Preview - This content has been restricted to logged in users only.
Very Thin PAMPA Membranes Indicate Higher Antipyrene Permeability but are Fragile and Contain Leaky Water Pores
Poster
Purpose. The aim of the study was to assess how thin PAMPA membrane barriers could be made before they become too fragile or leaky through water pores.
Conclusion. It was shown that antipyrine can have an elevated PAMPA permeability value (from 1 to 5 x10<sup>-6</sup> cm/s) in the plates with the thinnest barrier (BD), but it was clear that the plates were too leaky through water pores. This would limit the application to lipophilic molecules.